Evidence map›Paper›PMID 30066251›Full record

ArticleEuropean radiology2019

Quantitative dynamic contrast-enhanced MR imaging shows widespread blood-brain barrier disruption in mild traumatic brain injury patients with post-concussion syndrome.

Roh-Eul Yoo, Seung Hong Choi, Byung-Mo Oh, Sang Do Shin, Eun Jung Lee, Dong Jae Shin, Sang Won Jo, Koung Mi Kang, Tae Jin Yun, Ji-Hoon Kim and 1 more

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Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
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  3. Review
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  5. Article
  6. Review
  7. Blood-brain barrier disruption imaging in postoperative cerebral hyperperfusion syndrome using DCE-MRI.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Repetitive mTBI is associated with age-related reductions in cerebral blood flow but not cortical thickness.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Roh-Eul YooDepartment of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, 28, Yongon-dong, Chongno-gu, Seoul, 110-744, Korea.
Seung Hong ChoiDepartment of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, 28, Yongon-dong, Chongno-gu, Seoul, 110-744, Korea. verocay@snuh.org.ORCID http://orcid.org/0000-0001-8985-8473
Byung-Mo OhDepartment of Rehabilitation Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 28, Yongon-dong, Chongno-gu, Seoul, 110-744, Korea.
Sang Do ShinDepartment of Emergency Medicine, Seoul National University College of Medicine, 28, Yongon-dong, Chongno-gu, Seoul, 110-744, Korea.
Eun Jung LeeDepartment of Radiology, Chung-Ang University Hospital, Seoul, Korea.
Dong Jae ShinDepartment of Radiology, Seran General Hospital, Seoul, Korea.
Sang Won JoDepartment of Radiology, Kangbuk Samsung Hospital, Seoul, Korea.
Koung Mi KangDepartment of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, 28, Yongon-dong, Chongno-gu, Seoul, 110-744, Korea.
Tae Jin YunDepartment of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, 28, Yongon-dong, Chongno-gu, Seoul, 110-744, Korea.
Ji-Hoon KimDepartment of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, 28, Yongon-dong, Chongno-gu, Seoul, 110-744, Korea.
Chul-Ho SohnDepartment of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, 28, Yongon-dong, Chongno-gu, Seoul, 110-744, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo explore the utility of dynamic contrast-enhanced (DCE) MR imaging for quantitative analysis of blood-brain barrier disruption in mild traumatic brain injury (mTBI) patients with post-concussion syndrome (PCS).

methodsForty-four consecutive patients with PCS after mTBI and 32 controls were included in this retrospective study. K

resultsThe median v

conclusionsmTBI patients with PCS had higher K KEY POINTS: • mTBI patients with PCS had higher permeability than controls at T2 hyperintense WM lesions on DCE MR imaging. • mTBI patients with PCS had higher permeability than controls also at NAWM and predilection sites for DAI. • BBB disruption may be implicated in the development of PCS in mTBI patients.

Indexed as

AdultAgedAged, 80 and overBlood-Brain BarrierBrain Injuries, TraumaticFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedNeuropsychological TestsPost-Concussion SyndromeRetrospective StudiesWhite MatterYoung AdultBlood-brain barrierMagnetic resonance imagingPerfusionPermeabilityPost-concussion syndrome (PCS)

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.