Evidence map›Paper›PMID 30066185›Full record

Observational studyAdvances in therapy2018

Clinical Effectiveness of Budesonide/Formoterol Fumarate Easyhaler

Lilla Tamási, Maria Szilasi, Gabriella Gálffy

Open access · hybridAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Advances in therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Today's improvement in asthma treatment: role of MART and Easyhaler.Multidisciplinary respiratory medicine · 2020
    Article
  6. Article
  7. Article
  8. Observational
  9. EasyhalerDrugs in context · 2019
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Lilla TamásiDepartment of Pulmonology, Semmelweis University, Budapest, Hungary. tamasi.lilla@med.semmelweis-univ.hu.
Maria SzilasiDepartment of Pulmonology, University of Debrecen, Debrecen, Hungary.
Gabriella GálffyPulmonary Hospital, Törökbálint, Hungary.
Semmelweis University · HUUniversity of Debrecen · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe effectiveness of inhaled therapies can be influenced by many factors, including the type of inhaler, which may have clinical implications. We report a real-world, multicenter, open-label, non-randomized, non-interventional study conducted by 200 pulmonologists across 200 centers in Hungary. The effectiveness of budesonide/formoterol inhalation therapy in daily clinical practice, delivered via the Bufomix Easyhaler

methodsEffectiveness was assessed after 12 weeks of treatment by spirometry, the Asthma Control Test, mini-Asthma Quality of Life Questionnaire, COPD Assessment Test and modified Medical Research Council dyspnea scale. Patient satisfaction with the Bufomix Easyhaler

resultsA total of 1498 patients with obstructive airway disease were evaluated (asthma: n = 621; COPD: n = 778; ACO: n = 99), of whom 455 (30.4%) were newly diagnosed inhaler-naïve patients and 1043 (69.6%) were switching from other inhalers. Significant improvements in lung function, disease control and health-related quality of life measures (all p ≤ 0.002) were reported after 12 weeks of Bufomix Easyhaler

conclusionTwelve weeks' treatment with the Bufomix Easyhaler

fundingOrion Corp., Orion Pharma.

Indexed as

Metered Dose InhalersPatient Reported Outcome MeasuresAdministration, InhalationAdultAgedBudesonide, Formoterol Fumarate Drug CombinationFemaleHumansMaleMiddle AgedPatient SatisfactionPulmonary Disease, Chronic ObstructiveQuality of LifeRespiratory Tract AbsorptionTreatment OutcomeBudesonide, Formoterol Fumarate Drug CombinationACOAsthmaBudesonide/formoterol Easyhaler®COPDEffectivenessReal-world studyRespiratory/pulmonary

Identifiers

PMID30066185
PMCPMC6096955
OpenAlexW2885604228

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.