ReviewBiological trace element research2019
Is Lithium a Micronutrient? From Biological Activity and Epidemiological Observation to Food Fortification.
Review in Biological trace element research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 111 citations in OpenAlex.
- Evaluating mineral biomarkers as mediators and moderators of behavioural improvements in a randomised controlled trial of multinutrients for children with attention-deficit/hyperactivity disorder.The British journal of nutrition · 2024Trial
- A Geometrically Transient Platform for Bioelectronic Implants.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Manifestations of Lithium Deficiency in the Human Body: What is Known to Date (A Narrative Review).Biological trace element research · 2026Review
- Lithium exposure in areas of the Western United States: Water and urinary levels in the Strong Heart Family Study.Journal of exposure science & environmental epidemiology · 2026Article
- Biodegradable Zn-Based Implants: Progress, Challenges, and Pathways toward Clinical Translation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Mll5 haploinsufficiency attenuates microglial phagocytosis through dysregulated TREM2-SGK3-GSK3β signaling and recapitulates ASD-like behaviors in mice.Nature communications · 2026Article
- A qualitative exploration of perspectives on taking lithium supplements.Therapeutic advances in psychopharmacology · 2026Article
- Empowering health with mushroom biofortification: nutritional and medicinal attributes.Journal of food science and technology · 2025Review
- Association Between Natural Lithium Exposure and Suicide Rate: An Ecological and Biomonitoring Study in Portugal.Nutrients · 2025Article
- Lithium in Drinking Water and its Potential Impact on Mental Health: A Review.Current medicinal chemistry · 2025Review
- The Use of Nutraceutical and Pharmacological Strategies in Murine Models of Autism Spectrum Disorder.Cells · 2024Review
- Dietary sucrose determines the regulatory activity of lithium on gene expression and lifespan inAging · 2024Article
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- Lithium Content and Its Nutritional Beneficence, Dietary Intake, and Impact on Human Health in Edibles from the Romanian Market.Foods (Basel, Switzerland) · 2024Article
- Lithium: how low can you go?International journal of bipolar disorders · 2024Article
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- Evaluation of potential human health risks associated with Li and their relationship with Na, K, Mg, and Ca in Romania's nationwide drinking water.Frontiers in public health · 2024Article
- A Fast-Forward Dilute-and-Shoot Multielement Method for Analysis of 33 Elements in Human Whole Blood, Serum, and Urine by Inductively Coupled Plasma Mass Spectrometry: A Streamlined Approach for Clinical Diagnostic and Biomonitoring.Journal of analytical methods in chemistry · 2024Article
- Lithium chloride treatments in free flying honey bee colonies: efficacy, brood survival, and within-colony distribution.Parasitology research · 2023Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lithium compounds have been widely used in psychopharmacology, particularly in the treatment of bipolar disorder. Their normothymic and neuroprotective properties when used at high doses have been well established. However, a number of observations suggest that environmentally relevant lithium doses may also exert beneficial health effects, leading to a decrease in the rate of suicides and levels of violence. Despite the fact that this element is not officially considered to be a micronutrient, some authors have suggested provisional recommended intakes set at 1000 μg/day for a 70-kg adult (14.3 μg/kg body weight). The present paper reviews the biological action of lithium, its bioavailability and metabolism, and content in different foodstuffs and water. It also assesses epidemiological data on potential correlations between lithium intake and suicide rate as well as examines the concept of fortifying food with this element as a strategy in the primary prevention of mood disorders and pre-suicidal syndrome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.