Evidence map›Paper›PMID 30065965›Full record

ArticleBioengineering & translational medicine2018

Scalable synthesis and validation of PAMAM dendrimer-

Rishi Sharma, Anjali Sharma, Siva P Kambhampati, Rajsekar Rami Reddy, Zhi Zhang, Jeffrey L Cleland, Sujatha Kannan, Rangaramanujam M Kannan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioengineering & translational medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 67 citations in OpenAlex.

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  20. Dendrimer-2PMPA Delays Muscle Function Loss and Denervation in a Murine Model of Amyotrophic Lateral Sclerosis.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Rishi SharmaCenter for Nanomedicine, Department of Ophthalmology Wilmer Eye Institute Johns Hopkins University School of Medicine Baltimore MD 21287.
Anjali SharmaCenter for Nanomedicine, Department of Ophthalmology Wilmer Eye Institute Johns Hopkins University School of Medicine Baltimore MD 21287.
Siva P KambhampatiCenter for Nanomedicine, Department of Ophthalmology Wilmer Eye Institute Johns Hopkins University School of Medicine Baltimore MD 21287.
Rajsekar Rami ReddyCenter for Nanomedicine, Department of Ophthalmology Wilmer Eye Institute Johns Hopkins University School of Medicine Baltimore MD 21287.
Zhi ZhangDept. of Anesthesiology and Critical Care Medicine Johns Hopkins University School of Medicine Baltimore MD 21287.
Jeffrey L ClelandAshvattha Therapeutics, LLC Baltimore MD 21218.
Sujatha KannanCenter for Nanomedicine, Department of Ophthalmology Wilmer Eye Institute Johns Hopkins University School of Medicine Baltimore MD 21287.
Rangaramanujam M KannanCenter for Nanomedicine, Department of Ophthalmology Wilmer Eye Institute Johns Hopkins University School of Medicine Baltimore MD 21287.
Johns Hopkins University · USJohns Hopkins Medicine · USIo Therapeutics (United States) · US

Funding

Postnatal combination therapy for cerebral palsyR01HD076901 · NICHD · JOHNS HOPKINS UNIVERSITY · PI RANGARAMANUJAM, KANNAN · 2014 to 2018
$1.7M
NICHD NIH HHS R01 HD076901
6 · The paper itself

Abstract

Dendrimer-

Indexed as

activated microglia targetingantioxidantdendrimer‐drug‐conjugateN‐acetyl cysteineneuroinflammationPAMAM‐hydroxyl dendrimerscalable synthesis

Identifiers

PMID30065965
PMCPMC6063872
OpenAlexW2800050500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.