Evidence map›Paper›PMID 30065873›Full record

ArticlePeerJ2018

Mayram Hacioglu, Ayse Seher Birteksoz Tan, Sibel Dosler, Nese Inan, Gulten Otuk

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Rational selection of antifungal drugs to propose a new formulation strategy to control Candida biofilm formation on venous catheters.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mayram HaciogluDepartment of Pharmaceutical Microbiology, Istanbul University, Istanbul, Turkey.
Ayse Seher Birteksoz TanDepartment of Pharmaceutical Microbiology, Istanbul University, Istanbul, Turkey.
Sibel DoslerDepartment of Pharmaceutical Microbiology, Istanbul University, Istanbul, Turkey.
Nese InanDepartment of Microbiology, Faculty of Medicine, Istanbul Bilim University, Istanbul, Turkey.
Gulten OtukDepartment of Pharmaceutical Microbiology, Istanbul University, Istanbul, Turkey.
Istanbul University · TRIstanbul Bilim University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsIn this study, activities of antifungal agents alone and in combination with tigecycline against planktonic cells and mature and developing biofilms of

resultsAmphotericin B and echinocandins were found to be the most effective agents against mature biofilms, whereas the least effective agent was fluconazole. Furthermore, the most effective anti-fungal monotherapies against biofilm formation were amphotericin B and anidulafungin, and the least effective monotherapy was itraconazole. The combination of tigecycline and amphotericin B yielded synergistic effects, whereas combinations containing itraconazole yielded antagonist effects against planktonic cells. The combination of tigecycline and caspofungin exhibited maximum efficacy against mature biofilms, whereas combinations containing itraconazole exhibited minimal effects. Combinations of tigecycline with amphotericin B or anidulafungin were highly effective against DISCUSSION: In summary, tigecycline was highly active against

Indexed as

AntifungalBiofilmCandida albicansTigecyclineXTT

Identifiers

PMID30065873
PMCPMC6064206
OpenAlexW2884740022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.