Evidence map›Paper›PMID 30065850›Full record

ArticleZoological letters2018

Role of tyramine in calcium dynamics of GABAergic neurons and escape behavior in

Yuko Kagawa-Nagamura, Keiko Gengyo-Ando, Masamichi Ohkura, Junichi Nakai

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zoological letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Multiple sensory neurons mediate starvation-dependent aversive navigation inProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  4. Rhodopsin-based voltage imaging tools for use in muscles and neurons ofProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yuko Kagawa-Nagamura1Brain and Body System Science Institute, Saitama University, 255 Shimo-okubo, Sakura-ku, Saitama, 338-8570 Japan.
Keiko Gengyo-Ando1Brain and Body System Science Institute, Saitama University, 255 Shimo-okubo, Sakura-ku, Saitama, 338-8570 Japan.ORCID 0000-0002-4904-9345
Masamichi Ohkura1Brain and Body System Science Institute, Saitama University, 255 Shimo-okubo, Sakura-ku, Saitama, 338-8570 Japan.
Junichi Nakai1Brain and Body System Science Institute, Saitama University, 255 Shimo-okubo, Sakura-ku, Saitama, 338-8570 Japan.
RIKEN Center for Brain Science · JPSaitama University · JP

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

backgroundTyramine, known as a "trace amine" in mammals, modulates a wide range of behavior in invertebrates; however, the underlying cellular and circuit mechanisms are not well understood. In the nematode

resultsUsing calcium imaging in freely moving

conclusionWe demonstrate that endogenous tyramine downregulates calcium levels in GABAergic RME motor neurons in the head via the tyramine receptor SER-2 during backward locomotion and omega turns. Our data suggest that this neuromodulation allows deep head bending during omega turns and plays a role in the escape behavior in

Indexed as

Caenorhabditis elegansCalcium imagingEscape behaviorNeuromodulationTyramine

Identifiers

PMID30065850
PMCPMC6062986
OpenAlexW2883489747

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.