Evidence map›Paper›PMID 30065715›Full record

ArticleFrontiers in microbiology2018

Phenanthrene Antibiotic Targets Bacterial Membranes and Kills

Bo-Chen Chen, Chang-Xin Lin, Ni-Pi Chen, Cheng-Xian Gao, Ying-Jie Zhao, Chao-Dong Qian

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Bo-Chen ChenInstitute of Molecular Medicine, College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Chang-Xin LinInstitute of Molecular Medicine, College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Ni-Pi ChenInstitute of Molecular Medicine, College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Cheng-Xian GaoInstitute of Molecular Medicine, College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Ying-Jie ZhaoCollege of Pharmaceutical Science, Zhejiang Chinese Medical University, Hangzhou, China.
Chao-Dong QianInstitute of Molecular Medicine, College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.
Zhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New classes of antibiotics with different mechanisms of action are urgently required for combating antimicrobial resistance. Blestriacin, a dihydro-biphenanthrene with significant antibacterial activity, was recently isolated from the fibrous roots of

Indexed as

antibioticbactericidal effectdihydro-biphenanthrenemembrane-damaging activitymode of actionnatural productStaphylococcus aureus

Identifiers

PMID30065715
PMCPMC6056686
OpenAlexW2883915510

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.