ArticleFrontiers in physiology2018
Cerebrovascular Compliance Within the Rigid Confines of the Skull.
Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- The time constant of the cerebral arterial bed: exploring age-related implications.Journal of clinical monitoring and computing · 2024Article
- Rapid changes in cerebrovascular compliance during vasovagal syncope.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024Article
- Impact of arterial stiffness on cerebrovascular function: a review of evidence from humans and preclincal models.American journal of physiology. Heart and circulatory physiology · 2024Review
- Pulsatile microvascular cerebral blood flow waveforms change with intracranial compliance and age.Neurophotonics · 2024Article
- Intracranial Pressure Dysfunction Following Severe Intracerebral Hemorrhage in Middle-Aged Rats.Translational stroke research · 2023Article
- Characterization of cerebral macro- and microvascular hemodynamics during transient hypotension.Journal of applied physiology (Bethesda, Md. : 1985) · 2023Article
- Personalised simulation of hemodynamics in cerebrovascular disease: lessons learned from a study of diagnostic accuracy.Frontiers in neurology · 2023Article
- Regulation of cerebrovascular compliance compared with forearm vascular compliance in humans: a pharmacological study.American journal of physiology. Heart and circulatory physiology · 2023Article
- Cerebrovascular impedance estimation with near-infrared and diffuse correlation spectroscopy.Neurophotonics · 2023Article
- Cerebrovascular Impedance as a Function of Cerebral Perfusion Pressure.IEEE open journal of engineering in medicine and biology · 2023Article
- Stiffness pulsation of the human brain detected by non-invasive time-harmonic elastography.Frontiers in bioengineering and biotechnology · 2023Article
- Neuroinflammation, Sleep, and Circadian Rhythms.Frontiers in cellular and infection microbiology · 2022Review
- Intracranial Compliance Assessed by Intracranial Pressure Pulse Waveform.Brain sciences · 2021Article
- Rapid changes in vascular compliance contribute to cerebrovascular adjustments during transient reductions in blood pressure in young, healthy adults.Journal of applied physiology (Bethesda, Md. : 1985) · 2020Article
- Cerebral arterial time constant calculated from the middle and posterior cerebral arteries in healthy subjects.Journal of clinical monitoring and computing · 2019Article
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Authors and funding
5 authors.
Funding
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Abstract
Pulsatile blood flow is generally mediated by the compliance of blood vessels whereby they distend locally and momentarily to accommodate the passage of the pressure wave. This freedom of the blood vessels to exercise their compliance may be suppressed within the confines of the rigid skull. The effect of this on the mechanics of pulsatile blood flow within the cerebral circulation is not known, and the situation is compounded by experimental access difficulties. We present an approach which we have developed to overcome these difficulties in a study of the mechanics of pulsatile cerebral blood flow. The main finding is that while the innate compliance of cerebral vessels is indeed suppressed within the confines of the skull, this is compensated somewhat by compliance provided by other "extravascular" elements within the skull. The net result is what we have termed "intracranial compliance," which we argue is more pertinent to the mechanics of pulsatile cerebral blood flow than is intracranial pressure.
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