Evidence map›Paper›PMID 30065611›Full record

ReviewCurrent genomics2018

Molecular Insights into Muscle Homeostasis, Atrophy and Wasting.

Bianca Maria Scicchitano, Gabriella Dobrowolny, Gigliola Sica, Antonio Musarò

Open access · greenAbstract readReview
In one paragraph

Review in Current genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Muscle Organoid and Assembloid Systems.Advances in experimental medicine and biology · 2025
    Review
  8. Article
  9. Bile Acids Alter the Autophagy and Mitogenesis in Skeletal Muscle Cells.Advances in experimental medicine and biology · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Identification ofNutrients · 2020
    Article
  17. Article
  18. Taurine Attenuates Catabolic Processes Related to the Onset of Sarcopenia.International journal of molecular sciences · 2020
    Article
  19. Nutrition and microRNAs: Novel Insights to Fight Sarcopenia.Antioxidants (Basel, Switzerland) · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Bianca Maria ScicchitanoIstituto di Istologia e Embriologia, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Agostino Gemelli, Largo Francesco Vito 1-00168, Roma, Italy.
Gabriella DobrowolnyCenter for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Rome, Italy.
Gigliola SicaIstituto di Istologia e Embriologia, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Agostino Gemelli, Largo Francesco Vito 1-00168, Roma, Italy.
Antonio MusaròCenter for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Rome, Italy.
Italian Institute of Technology · ITAgostino Gemelli University Polyclinic · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Muscle homeostasis is guaranteed by a delicate balance between synthesis and degradation of cell proteins and its alteration leads to muscle wasting and diseases. In this review, we describe the major anabolic pathways that are involved in muscle growth and homeostasis and the proteolytic systems that are over-activated in muscle pathologies. Modulation of these pathways comprises an attractive target for drug intervention.

Indexed as

Anabolic pathwaysDegradation of cell proteinsMuscle atrophyMuscle homeostasisMuscle pathologiesMuscle wasting

Identifiers

PMID30065611
PMCPMC6030854
OpenAlexW2782519305

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.