ArticleActa Cardiologica Sinica2018
Low Serum Adropin Levels are Associated with Coronary Slow Flow Phenomenon.
Article in Acta Cardiologica Sinica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- The relationship between high-sensitivity C-reactive protein and coronary slow flow: a systematic review and meta-analysis.Systematic reviews · 2026Pooled it
- Adropin modulates pancreatic cell proliferation and glutathione levels in an animal model of type 1 diabetes mellitus.Animal models and experimental medicine · 2025Article
- The value of diagnosing coronary slow flow based on epicardial adipose tissue radiomics in chest computed tomography.BMC medical imaging · 2025Article
- Association of fibrinogen-to-albumin ratio in patients with isolated coronary artery ectasia.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2025Article
- Predictors and clinical outcomes of slow flow phenomenon in diabetic patients with chronic coronary syndrome.BMC cardiovascular disorders · 2024Article
- Emerging Predictors by Non-HDL-C/HDL-C Ratio and Novel Biomarkers for Coronary Slow Flow Phenomenon.Acta Cardiologica Sinica · 2024Review
- Article
- Relationship between quantitative epicardial adipose tissue based on coronary computed tomography angiography and coronary slow flow.BMC cardiovascular disorders · 2023Article
- Adropin - A new player in energy regulation predicts long-term prognosis of patients with acute myocardial infarction.Heliyon · 2023Article
- Association between Serum Galectin-3 and Growth Differentiation Factor-15 Levels and Coronary Slow Flow Phenomenon.Acta Cardiologica Sinica · 2023Article
- Adropin's Role in Energy Homeostasis and Metabolic Disorders.International journal of molecular sciences · 2022Review
- The relationship between radial artery spasm and adropin levels in patients undergoing transradial coronary angiography.Journal of cardiovascular and thoracic research · 2022Article
- Association of C-Reactive Protein to Albumin Ratio in Patients with Isolated Coronary Artery Ectasia.Arquivos brasileiros de cardiologia · 2021Article
- The Relationship between Blood Viscosity and Isolated Coronary Artery Ectasia.Acta Cardiologica Sinica · 2019Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAdropin is a peptide hormone expressed in coronary artery endothelial cells, which plays a potential endothelial protective role. We sought to assess whether serum adropin levels are correlated with the coronary slow flow phenomenon (CSFP).
methodsWe enrolled 82 patients with angiographically confirmed CSFP and 184 age-matched controls. Serum adropin levels were measured by enzyme-linked immunosorbent assay (ELISA), and coronary flow rate was assessed using thrombolysis in myocardial infarction (TIMI) frame count (TFC). CSFP was defined as a corrected TIMI-TFC greater than two standard deviations from the normal range.
resultsSerum adropin levels were significantly lower in the CSFP patients (n = 82) than in the controls (n = 184) (4.03 ± 1.99 vs. 4.86 ± 1.88 ng/ml, p = 0.001). Multivariate logistic regression analysis revealed that serum adropin was the only independent negative predictor of CSFP (odds ratio 0.758, 95% confidence interval 0.647-0.888, p = 0.001). Serum adropin levels were independently and negatively correlated with mean TFC (r = -0.387, p < 0.001).
conclusionsWe demonstrated that decreased serum adropin levels were independently associated with the presence and severity of angiographically proven CSFP. These findings suggest that serum adropin may be a potential biomarker to provide valuable information regarding the prediction of CSFP.
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