ArticleScientific reports2018
GM-CSF driven myeloid cells in adipose tissue link weight gain and insulin resistance via formation of 2-aminoadipate.
Open access · goldAbstract read
In one paragraph
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 34 citations in OpenAlex.
- Immune-modulating effects of energy-restricted ketogenic diet in women with overweight and obesity: KETO-MINOX study.European journal of nutrition · 2026Trial
- The consumption of animal products is associated with plasma levels of alpha-aminoadipic acid (2-AAA).Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024Trial
- Depletion of myeloid-derived Zbtb46Journal of advanced research · 2026Article
- Mechanism and therapeutic prospects of adipose tissue B lymphocytes in obesity and obesity‑associated metabolic diseases (Review).Molecular medicine reports · 2026Review
- Whole-genome resequencing revealed genetic structure and specific breed identification loci of Ningxia Jingyuan chicken breed (Gallus gallus).BMC genomics · 2025Article
- Proarrhythmic Lipid Inflammatory Mediators: Mechanisms in Obesity Arrhythmias.Journal of cellular physiology · 2025Review
- Metabolite 2-aminoadipic acid: implications for metabolic disorders and therapeutic opportunities.Frontiers in pharmacology · 2025Review
- Therapeutic blockade of CCL17 in obesity-exacerbated osteoarthritic pain and disease.PloS one · 2025Article
- Sirtuin 1 regulates the phenotype and functions of dendritic cells through Ido1 pathway in obesity.Cell death & disease · 2024Article
- Postprandial metabolomics analysis reveals disordered serotonin metabolism in post-bariatric hypoglycemia.The Journal of clinical investigation · 2024Article
- Mitochondrial Alpha-Keto Acid Dehydrogenase Complexes: Recent Developments on Structure and Function in Health and Disease.Sub-cellular biochemistry · 2024Review
- Review
- Association of alpha-aminoadipic acid (2-AAA) with cardiometabolic risk factors in healthy and high-risk individuals.medRxiv : the preprint server for health sciences · 2023Article
- Association of alpha-aminoadipic acid with cardiometabolic risk factors in healthy and high-risk individuals.Frontiers in endocrinology · 2023Article
- Administration of Phosphonate Inhibitors of Dehydrogenases of 2-Oxoglutarate and 2-Oxoadipate to Rats Elicits Target-Specific Metabolic and Physiological Responses.Frontiers in chemistry · 2022Article
- Delayed Impact of 2-Oxoadipate Dehydrogenase Inhibition on the Rat Brain Metabolism Is Linked to Protein Glutarylation.Frontiers in medicine · 2022Article
- Adipose Tissue Dendritic Cells: Critical Regulators of Obesity-Induced Inflammation and Insulin Resistance.International journal of molecular sciences · 2021Review
- Cellular and Molecular Players in the Interplay between Adipose Tissue and Breast Cancer.International journal of molecular sciences · 2021Review
- Does Proteomic Mirror Reflect Clinical Characteristics of Obesity?Journal of personalized medicine · 2021Article
- CXCL9 secreted by tumor-associated dendritic cells up-regulates PD-L1 expression in bladder cancer cells by activating the CXCR3 signaling.BMC immunology · 2021Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Deanna L PlubellDepartment of Medicine, Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR, USA.ORCID 0000-0002-6580-8073
Alexandra M FentonDepartment of Medicine, Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR, USA.
Phillip A WilmarthProteomics Shared Resource, Oregon Health & Science University, Portland, OR, USA.
Paige BergstromDepartment of Medicine, Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR, USA.
Yuqi ZhaoDepartment of Integrative Biology and Physiology, University of California, Los Angeles, CA, USA.
Jessica MinnierDepartment of Medicine, Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR, USA.ORCID 0000-0002-3527-2757
Jay W HeineckeDepartment of Medicine, University of Washington, Seattle, WA, USA.
Xia YangDepartment of Integrative Biology and Physiology, University of California, Los Angeles, CA, USA.ORCID 0000-0002-3971-038X
Nathalie PamirDepartment of Medicine, Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR, USA. pamir@ohsu.edu.ORCID 0000-0002-2074-888X
Oregon Health & Science University · USUniversity of California, Los Angeles · USUniversity of Washington · US
Funding
Vector and Transgenic Mouse CoreP30DK017047 · NIDDK · UNIVERSITY OF WASHINGTON · PI Sakeneh Zraika · 1986 to 2026
$41.4MRole of Serum Amyloid A in Diabetic Vascular DiseaseP01HL092969 · NHLBI · UNIVERSITY OF WASHINGTON · PI BORNFELDT, KARIN E. · 2008 to 2019
$23.5MIdentification of the role of HDL function in human cardiovascular disease through proteomics and geneticsR01HL136373 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI PAMIR, NATHALIE · 2018 to 2022
$2.4MDHA Reverses Gene Network Signatures of Fructose-induced Metabolic SyndromeR01DK104363 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI YANG, XIA · 2015 to 2019
$2.4MAmerican Heart Association (American Heart Association, Inc.) 13SDG16940064American Heart Association (American Heart Association, Inc.) 13SDG17290032American Heart Association (American Heart Association, Inc.) 16POST31160044NHLBI NIH HHS P01 HL092969NHLBI NIH HHS R01 HL136373NIDDK NIH HHS P30 DK017047NIDDK NIH HHS R01 DK104363
Abstract
In a GM-CSF driven myeloid cell deficient mouse model (Csf2
Indexed as
Adipose TissueAdiposityAnimalsBody WeightCholesterolDietary FatsDiet, High-FatEnergy MetabolismGlucoseGranulocyte-Macrophage Colony-Stimulating FactorInsulinInsulin ResistanceKetone OxidoreductasesLipid MetabolismMaleMiceCholesterolDietary FatsGlucoseGranulocyte-Macrophage Colony-Stimulating FactorInsulinKetone OxidoreductasesTriglycerides
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.