Evidence map›Paper›PMID 30065171›Full record

ArticleMarine drugs2018

Characterization of the Jomthonic Acids Biosynthesis Pathway and Isolation of Novel Analogues in

Raúl García-Salcedo, Rubén Álvarez-Álvarez, Carlos Olano, Librada Cañedo, Alfredo F Braña, Carmen Méndez, Fernando de la Calle, José A Salas

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Mintaimycins, a Group of Novel Peptide Metabolites fromMolecules (Basel, Switzerland) · 2022
    Article
  6. TAR Cloning: Perspectives for Functional Genomics, Biomedicine, and Biotechnology.Molecular therapy. Methods & clinical development · 2019
    Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Raúl García-SalcedoDepartment of Functional Biology and University Institute of Oncology of Principado de Asturias (U.I.O.P.A), University of Oviedo, 33006 Oviedo (Asturias), Spain. raul.garcia.salcedo@gmx.com.
Rubén Álvarez-ÁlvarezDepartment of Functional Biology and University Institute of Oncology of Principado de Asturias (U.I.O.P.A), University of Oviedo, 33006 Oviedo (Asturias), Spain. ruben.alvarez.microbio@gmail.com.
Carlos OlanoDepartment of Functional Biology and University Institute of Oncology of Principado de Asturias (U.I.O.P.A), University of Oviedo, 33006 Oviedo (Asturias), Spain. olanocarlos@uniovi.es.ORCID 0000-0001-5440-3540
Librada CañedoDrug Discovery Area, PharmaMar S.A. Avda. de los Reyes 1, 28770 Colmenar Viejo (Madrid), Spain. lcanedo@pharmamar.com.ORCID 0000-0002-1273-4138
Alfredo F BrañaDepartment of Functional Biology and University Institute of Oncology of Principado de Asturias (U.I.O.P.A), University of Oviedo, 33006 Oviedo (Asturias), Spain. afb@uniovi.es.
Carmen MéndezDepartment of Functional Biology and University Institute of Oncology of Principado de Asturias (U.I.O.P.A), University of Oviedo, 33006 Oviedo (Asturias), Spain. cmendezf@uniovi.es.
Fernando de la CalleDrug Discovery Area, PharmaMar S.A. Avda. de los Reyes 1, 28770 Colmenar Viejo (Madrid), Spain. fdelacalle@pharmamar.com.ORCID 0000-0001-8161-8299
José A SalasInstitute for Health Research of Principado de Asturias (IHRPA), 33006 Oviedo (Asturias), Spain. jasalas@uniovi.es.ORCID 0000-0001-6495-3810
Universidad de Oviedo · ESPharmaMar (Spain) · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Jomthonic acids (JAs) are a group of natural products (NPs) with adipogenic activity. Structurally, JAs are formed by a modified β-methylphenylalanine residue, whose biosynthesis involves a methyltransferase that in

Indexed as

Amino AcidsBiological ProductsComputational BiologyGene Expression Regulation, BacterialMolecular StructureMultigene FamilyPhenylalanineStreptomycesAmino AcidsBiological Productsjomthonic acidPhenylalaninebiosynthesis gene clusterheterologous expressionmolecular elicitationnonribosomal peptide synthetasepolyketide synthase

Identifiers

PMID30065171
PMCPMC6117699
OpenAlexW2885383158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.