Evidence map›Paper›PMID 30065115›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Directly light-regulated binding of RGS-LOV photoreceptors to anionic membrane phospholipids.

Spencer T Glantz, Erin E Berlew, Zaynab Jaber, Benjamin S Schuster, Kevin H Gardner, Brian Y Chow

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
9.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 76 citations in OpenAlex.

  1. Article
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  7. Mining Genetically Encoded Biosensors from Filamentous Fungi.Journal of fungi (Basel, Switzerland) · 2026
    Review
  8. Article
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  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Rapid optogenetic clustering of a cytoplasmic BcLOV4 variant.bioRxiv : the preprint server for biology · 2023
    Article
  20. Optogenetic clustering and membrane translocation of the BcLOV4 photoreceptor.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Spencer T GlantzDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104.
Erin E BerlewDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104.
Zaynab JaberStructural Biology Initiative, Advanced Science Research Center, The Graduate Center, City University of New York, New York, NY 10031.
Benjamin S SchusterDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104.ORCID 0000-0002-6468-8081
Kevin H GardnerStructural Biology Initiative, Advanced Science Research Center, The Graduate Center, City University of New York, New York, NY 10031.ORCID 0000-0002-8671-2556
Brian Y ChowDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104; bchow@seas.upenn.edu.
University of Pennsylvania · USThe Graduate Center, CUNY · US

Funding

Summer Undergraduate Research Support - Ms. Anastasiia FisiukR01GM106239 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI GARDNER, KEVIN H · 2013 to 2024
$4.5M
Training Program in Neuroengineering and MedicineT32NS091006 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Brian Litt · 2015 to 2026
$4.1M
Ultrafast Genetically Encoded Voltage Indicators Designed from First PrinciplesR01NS101106 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI DISCHER, BOHDANA · 2017 to 2021
$2.2M
Optogenetic Toolbox for Studying Regulators of G-Protein Signaling in AddictionR21DA040434 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI CHOW, BRIAN Y · 2015 to 2016
$385k
Engineering protein vesicles for drug delivery applicationsF32GM119430 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI SCHUSTER, BENJAMIN S · 2016 to 2018
$142k
NIDA NIH HHS R21 DA040434NIGMS NIH HHS F32 GM119430NIGMS NIH HHS R01 GM106239NINDS NIH HHS R01 NS101106NINDS NIH HHS T32 NS091006
6 · The paper itself

Abstract

We report natural light-oxygen-voltage (LOV) photoreceptors with a blue light-switched, high-affinity (

Indexed as

BotrytisFungal ProteinsMembrane ProteinsPhospholipidsFungal ProteinsMembrane ProteinsPhospholipidslight–oxygen–voltage domainLOVoptogeneticsphotobiology

Identifiers

PMID30065115
PMCPMC6099885
OpenAlexW2886440289

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.