Evidence map›Paper›PMID 30065093›Full record

ArticlemBio2018

Nontypeable Haemophilus influenzae Lipooligosaccharide Expresses a Terminal Ketodeoxyoctanoate

Michael A Apicella, Jeremy Coffin, Margaret Ketterer, Deborah M B Post, Christopher J Day, Freda E-C Jen, Michael P Jennings

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Panel 8: Vaccines and immunology.International journal of pediatric otorhinolaryngology · 2020
    Review
  9. Article
  10. Review
  11. Analysis of Invasive NontypeableInfection and immunity · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Michael A Apicella *Department of Microbiology and Immunology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa, USA michael-apicella@uiowa.edu.
Jeremy Coffin *Department of Microbiology and Immunology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa, USA.
Margaret KettererDepartment of Microbiology and Immunology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa, USA.
Deborah M B PostBuck Institute for Age Research, Novato, California, USA.
Christopher J DayInstitute for Glycomics, Griffith University, Gold Coast Campus, Southport, Queensland, Australia.
Freda E-C JenInstitute for Glycomics, Griffith University, Gold Coast Campus, Southport, Queensland, Australia.
Michael P JenningsInstitute for Glycomics, Griffith University, Gold Coast Campus, Southport, Queensland, Australia.
Griffith University · AUUniversity of Iowa · USBuck Institute for Research on Aging · US

Funding

Vector Core-Core 2P30DK054759 · NIDDK · UNIVERSITY OF IOWA · PI Alejandro Antonio Pezzulo · 1998 to 2026
$30.5M
LIPOOLIGOSACCHARIDES OF HAEMOPHILUS INFLUENZAER01AI024616 · NIAID · UNIVERSITY OF IOWA · PI APICELLA, MICHAEL A. · 1988 to 2014
$6.0M
Otitis media: role of epigenetic regulation on NTHI pathogenesis and optimal vaccine designR01DC015688 · NIDCD · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI BAKALETZ, LAUREN O, JENNINGS, MICHAEL PAUL · 2016 to 2020
$2.2M
LIPOOLIGOSACCHARIDES OF HAEMOPHILUS INFLUENZAER37AI024616 · NIAID · UNIVERSITY OF IOWA · PI APICELLA, MICHAEL A. · 1994 to 2003
$1.9M
H. influenzae: Role of Sialic Acid in VirulenceR56AI024616 · NIAID · UNIVERSITY OF IOWA · PI APICELLA, MICHAEL A. · 2009 to 2009
$649k
NIAID NIH HHS R01 AI024616NIAID NIH HHS R37 AI024616NIAID NIH HHS R56 AI024616NIDCD NIH HHS R01 DC015688NIDDK NIH HHS P30 DK054759
6 · The paper itself

Abstract

Nontypeable

Indexed as

Antibodies, BacterialCaprylatesHaemophilus influenzaeLipopolysaccharidesMicrobial ViabilityN-Acetylneuraminic AcidAntibodies, BacterialCaprylateslipid-linked oligosaccharidesLipopolysaccharidesN-Acetylneuraminic Acidbactericidal activitybiofilmELISAketo-deoxyoctanoatelipooligosaccharidenontypeable Haemophilus influenzaesialic acidvaccine

Identifiers

PMID30065093
PMCPMC6069110
OpenAlexW2887417740

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.