Evidence map›Paper›PMID 30065024›Full record

ArticleRNA (New York, N.Y.)2018

Dynamic temperature-sensitive A-to-I RNA editing in the brain of a heterothermic mammal during hibernation.

Kent A Riemondy, Austin E Gillen, Emily A White, Lori K Bogren, Jay R Hesselberth, Sandra L Martin

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
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  11. RNA editing: Expanding the potential of RNA therapeutics.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kent A RiemondyRNA Bioscience Initiative, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045, USA.ORCID 0000-0003-0750-1273
Austin E GillenRNA Bioscience Initiative, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045, USA.ORCID 0000-0003-2928-6308
Emily A WhiteRNA Bioscience Initiative, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045, USA.
Lori K BogrenDepartment of Cell and Developmental Biology.ORCID 0000-0001-9023-6639
Jay R HesselberthRNA Bioscience Initiative, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045, USA.ORCID 0000-0002-6299-179X
Sandra L MartinRNA Bioscience Initiative, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045, USA.ORCID 0000-0002-6274-1475
University of Colorado Anschutz Medical Campus · US

Funding

University of Colorado Cancer Center Support Grant - Lung Cancer Patient-Derived Xenografts with Autologous Human Immune SystemsP30CA046934 · NCI · UNIVERSITY OF COLORADO DENVER · PI James V Degregori · 1988 to 2026
$117.0M
Nanopore analysis of transfer RNA forms and functionsR35GM119550 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI Jay R Hesselberth · 2016 to 2026
$4.5M
Biomarkers for the two phase switches of mammalian hibernationR01HL089049 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI MARTIN, SANDRA L · 2008 to 2011
$1.5M
Examining the hibernating brain for temperature-sensitive RNA editingR21NS088315 · NINDS · UNIVERSITY OF COLORADO DENVER · PI MARTIN, SANDRA L · 2015 to 2016
$422k
NCI NIH HHS P30 CA046934NHLBI NIH HHS R01 HL089049NINDS NIH HHS R21 NS088315
6 · The paper itself

Abstract

RNA editing diversifies genomically encoded information to expand the complexity of the transcriptome. In ectothermic organisms, including

Indexed as

RNA EditingTemperatureAnimalsBrainEvolution, MolecularGene Expression ProfilingGene Expression RegulationHibernationMammalsRNA, MessengerSciuridaeTorporTranscriptomeRNA, MessengerADARhibernationRNA-editingtemperature adaptation

Identifiers

PMID30065024
PMCPMC6191720
OpenAlexW2951863251

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.