ArticleJMIR mental health2018
An Embodied Conversational Agent for Unguided Internet-Based Cognitive Behavior Therapy in Preventative Mental Health: Feasibility and Acceptability Pilot Trial.
Article in JMIR mental health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 4 syntheses or guidelines pooled it, 119 citations in OpenAlex.
- Efficacy, User Engagement, and Acceptability of Cognitive Behavioral Therapy-Oriented Psychological Chatbots for Adults With Depressive and/or Anxiety Symptoms: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2026Pooled it
- Conversational Agent Interventions for Mental Health Problems: Systematic Review and Meta-analysis of Randomized Controlled Trials.Journal of medical Internet research · 2023Pooled it
- Changes to the Psychiatric Chatbot Landscape: A Systematic Review of Conversational Agents in Serious Mental Illness: Changements du paysage psychiatrique des chatbots: une revue systématique des agents conversationnels dans la maladie mentale sérieuse.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2021Pooled it
- Effectiveness and Safety of Using Chatbots to Improve Mental Health: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2020Pooled it
- Bridging Technology and Pretest Genetic Services: Quantitative Study of Chatbot Interaction Patterns, User Characteristics, and Genetic Testing Decisions.Journal of medical Internet research · 2025Trial
- Effectiveness of Topic-Based Chatbots on Mental Health Self-Care and Mental Well-Being: Randomized Controlled Trial.Journal of medical Internet research · 2025Trial
- Effects of a Chatbot-Based Intervention on Stress and Health-Related Parameters in a Stressed Sample: Randomized Controlled Trial.JMIR mental health · 2024Trial
- Mental Health Chatbot for Young Adults With Depressive Symptoms During the COVID-19 Pandemic: Single-Blind, Three-Arm Randomized Controlled Trial.Journal of medical Internet research · 2022Trial
- Embodied Intelligence Applications in Health Care Populations: Scoping Review.Journal of medical Internet research · 2026Article
- The effectiveness of CBT-based NLP-enabled AI conversational agents for mental health intervention: a systematic review and meta-analysis.NPJ digital medicine · 2026Article
- Current Landscape of Mental Health Conversational Agents From a Trauma-Informed Care Lens: Scoping Review.JMIR mental health · 2026Article
- World Health Organization Evidence-Based Self-Help Plus Intervention for Stress Management via Chatbot: Protocol for Adaptation to a Tech-Enabled Model.JMIR research protocols · 2025Article
- Evaluating the Potential and Pitfalls of AI-Powered Conversational Agents as Humanlike Virtual Health Carers in the Remote Management of Noncommunicable Diseases: Scoping Review.Journal of medical Internet research · 2024Article
- Evaluation framework for conversational agents with artificial intelligence in health interventions: a systematic scoping review.Journal of the American Medical Informatics Association : JAMIA · 2024Article
- Development of an online service for coping with spousal loss by means of human-centered and stakeholder-inclusive design: the case of LEAVES.Death studies · 2024Article
- CuentosIE: can a chatbot about "tales with a message" help to teach emotional intelligence?PeerJ. Computer science · 2024Article
- An Integrative Survey on Mental Health Conversational Agents to Bridge Computer Science and Medical Perspectives.Proceedings of the Conference on Empirical Methods in Natural Language Processing. Conference on Empirical Methods in Natural Language Processing · 2023Article
- The Use of Voice Assistant for Psychological Assessment Elicits Empathy and Engagement While Maintaining Good Psychometric Properties.Behavioral sciences (Basel, Switzerland) · 2023Article
- Article
- Evaluating Conversational Agents for Mental Health: Scoping Review of Outcomes and Outcome Measurement Instruments.Journal of medical Internet research · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecent years have seen an increase in the use of internet-based cognitive behavioral therapy in the area of mental health. Although lower effectiveness and higher dropout rates of unguided than those of guided internet-based cognitive behavioral therapy remain critical issues, not incurring ongoing human clinical resources makes it highly advantageous.
objectiveCurrent research in psychotherapy, which acknowledges the importance of therapeutic alliance, aims to evaluate the feasibility and acceptability, in terms of mental health, of an application that is embodied with a conversational agent. This application was enabled for use as an internet-based cognitive behavioral therapy preventative mental health measure.
methodsAnalysis of the data from the 191 participants of the experimental group with a mean age of 38.07 (SD 10.75) years and the 263 participants of the control group with a mean age of 38.05 (SD 13.45) years using a 2-way factorial analysis of variance (group × time) was performed.
resultsThere was a significant main effect (P=.02) and interaction for time on the variable of positive mental health (P=.02), and for the treatment group, a significant simple main effect was also found (P=.002). In addition, there was a significant main effect (P=.02) and interaction for time on the variable of negative mental health (P=.005), and for the treatment group, a significant simple main effect was also found (P=.001).
conclusionsThis research can be seen to represent a certain level of evidence for the mental health application developed herein, indicating empirically that internet-based cognitive behavioral therapy with the embodied conversational agent can be used in mental health care. In the pilot trial, given the issues related to feasibility and acceptability, it is necessary to pursue higher quality evidence while continuing to further improve the application, based on the findings of the current research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.