ArticleBMC research notes2018
Pattern of antibiotics use, incidence and predictors of surgical site infections in a Tertiary Care Teaching Hospital.
Article in BMC research notes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence, risk factors, and antimicrobial resistance of endemic healthcare-associated infections in Africa: a systematic review and meta-analysis.BMC infectious diseases · 2024Pooled it
- Surgical site infection and its associated factors in Ethiopia: a systematic review and meta-analysis.BMC surgery · 2020Pooled it
- Antimicrobial stewardship in practice: determinants of prescription behaviour and developing interventions to improve surgical prophylaxis in a Rwandan tertiary hospital-a mixed methods study using the behaviour change wheel.Antimicrobial resistance and infection control · 2026Article
- Surgical Antibiotic Prophylaxis Utilization and Predictors of Surgical Site Infections at Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia: Prospective Cohort Study.BioMed research international · 2026Article
- Article
- Bacterial profile of surgical site infection and antimicrobial resistance patterns in Ethiopia: a multicentre prospective cross-sectional study.Annals of clinical microbiology and antimicrobials · 2023Article
- Surgical site infection and antimicrobial prophylaxis prescribing profile, and its determinants among hospitalized patients in Northeast Ethiopia: a hospital based cross-sectional study.Scientific reports · 2023Article
- Time to development of surgical site infection and its predictors among general surgery patients admitted at specialized hospitals in Amhara region, northwest Ethiopia: a prospective follow-up study.BMC infectious diseases · 2023Article
- Ongoing Efforts to Improve Antimicrobial Utilization in Hospitals among African Countries and Implications for the Future.Antibiotics (Basel, Switzerland) · 2022Article
- Appropriateness of surgical antimicrobial prophylaxis in a teaching hospital in Ghana: findings and implications.JAC-antimicrobial resistance · 2022Article
- Article
- Assessment of Bacterial Profiles and Antimicrobial Susceptibility Pattern of Isolates Among Patients Diagnosed with Surgical Site Infections at Mizan-Tepi University Teaching Hospital, Southwest Ethiopia: A Prospective Observational Cohort Study.Infection and drug resistance · 2022Article
- Choice of Antimicrobials in Surgical Prophylaxis - Overuse and Surgical Site Infection Outcomes from a Tertiary-Level Care Hospital.Frontiers in pharmacology · 2022Article
- The impact of cefuroxime prophylaxis on human intestinal microbiota in surgical oncological patients.Frontiers in microbiomes · 2022Article
- Current practices and evaluation of barriers and facilitators to surgical site infection prevention measures in Jimma, Ethiopia.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2021Article
- Key Issues Surrounding Appropriate Antibiotic Use for Prevention of Surgical Site Infections in Low- and Middle-Income Countries: A Narrative Review and the Implications.International journal of general medicine · 2021Review
- Supporting global antimicrobial stewardship: antibiotic prophylaxis for the prevention of surgical site infection in low- and middle-income countries (LMICs): a scoping review and meta-analysis.JAC-antimicrobial resistance · 2020Article
- Evaluation of Surgical Antimicrobial Prophylaxis and Incidence of Surgical Site Infection at Borumeda Hospital, Northeast Ethiopia: Retrospective Cross-Sectional Study.Drug, healthcare and patient safety · 2020Article
- Surgical Site Infections and Prophylaxis Antibiotic Use in the Surgical Ward of Public Hospital in Western Ethiopia: A Hospital-Based Retrospective Cross-Sectional Study.Infection and drug resistance · 2020Article
- Ceftriaxone use in a tertiary care hospital in Kilimanjaro, Tanzania: A need for a hospital antibiotic stewardship programme.PloS one · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveSurgical site infections (SSIs) were the most common healthcare-associated infection mainly in developing countries. Inappropriate use of surgical antibiotic prophylaxis, in terms of antibiotic choice, timing, and duration, can lead to the selection of resistant microorganisms and high costs. The aim of this study was to investigate the pattern of antibiotic use, incidence and predictors of SSIs at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia.
resultsFrom 131 patients, 55.7% were male study participants. Ninety (68.7%) patients received preoperative prophylaxis. Ceftriaxone was the most 76 (84.5%) prescribed agent for prophylaxis. Twenty-seven (20.6%) patients developed surgical site infection. Previous surgery AOR = 3.22 (95% CI [1.14-9.13]) and alcohol use AOR = 7.04 (95% CI [2.56-23.12, p = 0.000]) were independent predictors of SSIs in multivariate logistic regression analysis.
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