Evidence map›Paper›PMID 30064485›Full record

ArticleBMC research notes2018

Clinicopathologic features of invasive metaplastic and micropapillary breast carcinoma: comparison with invasive ductal carcinoma of breast.

Atif Ali Hashmi, Saher Aijaz, Raeesa Mahboob, Saadia Mehmood Khan, Muhammad Irfan, Narisa Iftikhar, Mariam Nisar, Maham Siddiqui, Muhammad Muzzammil Edhi, Naveen Faridi and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Atif Ali HashmiLiaquat National Hospital and Medical College, Karachi, Pakistan.
Saher AijazShaheed Zulfiqar Ali Bhutto Institute of Science and Technology, Karachi, Pakistan.
Raeesa MahboobLiaquat National Hospital and Medical College, Karachi, Pakistan.
Saadia Mehmood KhanLiaquat National Hospital and Medical College, Karachi, Pakistan.
Muhammad IrfanDepartment of Statistics, Liaquat National Hospital and Medical College, Karachi, Pakistan.
Narisa IftikharLiaquat National Hospital and Medical College, Karachi, Pakistan.
Mariam NisarLiaquat National Hospital and Medical College, Karachi, Pakistan.
Maham SiddiquiAga Khan University, Karachi, Pakistan.
Muhammad Muzzammil EdhiDepartment of Surgery, Brown University, Providence, RI, USA.
Naveen FaridiDepartment of Pathology, National Hospital and Medical College, Karachi, Pakistan.
Amir KhanDepartment of Medicine, Kandahar University, Kandahar, Afghanistan. dramirkhan04@gmail.com.ORCID http://orcid.org/0000-0002-8763-7690
Liaquat National Hospital · PKAga Khan University · PKBrown University · USKandahar University · AFShaheed Zulfiqar Ali Bhutto Institute of Science and Technology · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to determine the frequency of metaplastic breast carcinoma and invasive micropapillary carcinoma in our population and also to compare the clinico-pathologic features of metaplastic breast carcinoma and invasive micropapillary carcinoma with invasive ductal carcinoma, not otherwise specified (IDC, NOS).

results86.9% of the cases were identified as ductal carcinoma, NOS, while 2.2% were metaplastic and 0.76% cases were micropapillary carcinoma. Metaplastic carcinomas were found to be of higher grade as compared to IDC, NOS as 81% of metaplastic carcinoma were grade III compared to 35% IDC, NOS. 79% of metaplastic carcinoma were ER negative and 86% were PR negative, respectively as compared to ductal carcinoma NOS, which were 40% ER negative and 54% were PR. Similarly, 86.7% micropapillary cancers were ER positive and 73.3% were PR positive. Moreover, 66.7% micropapillary carcinoma showed nodal metastasis and 77.8% showed lymphovascular invasion, which was significantly higher than that of IDC, NOS micropapillary and metaplastic carcinomas accounts for less than 2 and 1% of the breast cancer burden in our population and highly correlates with poor prognosis parameters therefore, require more intensive management in our population.

Indexed as

Lymphatic MetastasisAdultAgedBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, PapillaryFemaleHumansMiddle AgedNeoplasm InvasivenessBreast cancerERHer2neuMetaplastic carcinomaMicropapillary carcinomaPR

Identifiers

PMID30064485
PMCPMC6069771
OpenAlexW2887897388

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.