ArticleParasites & vectors2018
Comparing four diagnostic tests for Giardia duodenalis in dogs using latent class analysis.
Article in Parasites & vectors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed, 34 citations in OpenAlex.
- Risk factors for recurrence of Giardia duodenalis infection in dogs: a case-control study.The Journal of small animal practice · 2026Article
- Outcome of parasitological examinations in cats in Germany: a retrospective survey.Parasitology research · 2025Article
- Feline Coronavirus Prevalence in 493 Cats With Chronic Diarrhea.Journal of veterinary internal medicine · 2025Article
- The Influence ofVeterinary sciences · 2023Article
- The opportunistic protist,Emerging microbes & infections · 2023Article
- Molecular Detection and Distribution ofTransboundary and emerging diseases · 2023Article
- Prevalence and genotypes ofVeterinary research forum : an international quarterly journal · 2023Article
- Burden and Epidemiology of Human IntestinalTropical medicine and infectious disease · 2022Review
- Latent class analysis of behavior across dog breeds reveal underlying temperament profiles.Scientific reports · 2022Article
- Article
- Lack of efficacy of fenbendazole against Giardia duodenalis in a naturally infected population of dogs in France.Parasite (Paris, France) · 2022Article
- Real-Time PCR for Molecular Detection of Zoonotic and Non-ZoonoticMicroorganisms · 2021Article
- Effectiveness of Fenbendazole and Metronidazole AgainstFrontiers in veterinary science · 2021Article
- Giardia duodenalis multi-locus genotypes in dogs with different levels of synanthropism and clinical signs.Parasites & vectors · 2020Article
- Rapid on-site diagnosis of canine giardiosis: time versus performance.Parasites & vectors · 2020Article
- Whole-genome sequencing of dog-specific assemblages C and D ofMicrobial genomics · 2019Article
- Coprological detection of equine nematodes among slaughtered donkeys (Veterinary world · 2019Article
- Host factors associated with Giardia duodenalis infection in dogs across multiple diagnostic tests.Parasites & vectors · 2019Article
- Comparative cost-effectiveness of immunoassays and FLOTAC for diagnosing Giardia spp. infection in dogs.Parasites & vectors · 2019Article
- Comparison of multiplexed-tandem real-time PCR panel with reference real-time PCR molecular diagnostic assays for detection of Giardia intestinalis and Tritrichomonas foetus in cats.Veterinary parasitology · 2019Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo accurately diagnose giardiosis in dogs, knowledge of diagnostic test characteristics and expected prevalence are required. The aim of this work was to estimate test characteristics (sensitivity and specificity) of four commonly used diagnostic tests for detection of Giardia duodenalis in dogs.
methodsFecal samples from 573 dogs originating from four populations (household dogs, shelter dogs, hunting dogs and clinical dogs) were examined with centrifugation sedimentation flotation (CSF) coproscopical analysis, direct immunofluorescence assay (DFA, Merifluor Cryptosporidium/Giardia®), a rapid enzyme immunochromatographic assay (IDEXX SNAP Giardia®) and qPCR (SSU rDNA) for presence of G. duodenalis. Bayesian latent class analysis was used to determine test performance characteristics and to estimate G. duodenalis prevalence of each of the four dog populations.
resultsAll tests were highly specific. IDEXX SNAP Giardia® showed the highest specificity (99.6%) and qPCR the lowest (85.6%). The sensitivities were much more variable, with qPCR showing the highest (97.0%) and CSF the lowest (48.2%) sensitivity. DFA was more sensitive than IDEXX SNAP Giardia®, but slightly less specific. Prevalences of G. duodenalis differed substantially between populations, with the hunting dogs showing the highest G. duodenalis prevalence (64.9%) and the household dogs the lowest (7.9%).
conclusionsThis study identifies qPCR as a valuable screening tool because of its high sensitivity, whereas methods using microscopy for cyst identification or cyst wall detection should be used in situations where high specificity is required. G. duodenalis is a prevalent gastro-intestinal parasite in Dutch dogs, especially in dogs living in groups (hunting and shelter dogs) and clinical dogs.
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