Evidence map›Paper›PMID 30064430›Full record

ArticleBiomedical engineering online2018

Wound healing of human embryonic stem cell-derived retinal pigment epithelial cells is affected by maturation stage.

Amna E Abu Khamidakh, Alejandra Rodriguez-Martinez, Kai Kaarniranta, Anne Kallioniemi, Heli Skottman, Jari Hyttinen, Kati Juuti-Uusitalo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical engineering online, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Amna E Abu KhamidakhFaculty of Biomedical Sciences and Engineering, BioMediTech, Tampere University of Technology, Arvo Ylpön Katu 34, Tampere, Finland.
Alejandra Rodriguez-MartinezFaculty of Medical and Life Sciences, BioMediTech, University of Tampere, Arvo Ylpön Katu 34, Tampere, Finland.
Kai KaarnirantaDepartment of Ophthalmology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.
Anne KallioniemiFaculty of Medical and Life Sciences, BioMediTech, University of Tampere, Arvo Ylpön Katu 34, Tampere, Finland.
Heli SkottmanFaculty of Medical and Life Sciences, BioMediTech, University of Tampere, Arvo Ylpön Katu 34, Tampere, Finland.
Jari HyttinenFaculty of Biomedical Sciences and Engineering, BioMediTech, Tampere University of Technology, Arvo Ylpön Katu 34, Tampere, Finland.
Kati Juuti-UusitaloFaculty of Medical and Life Sciences, BioMediTech, University of Tampere, Arvo Ylpön Katu 34, Tampere, Finland. kati.juuti-uusitalo@staff.uta.fi.ORCID http://orcid.org/0000-0003-2275-5562
Tampere University · FIUniversity of Eastern Finland · FI

Funding

Luonnontieteiden ja Tekniikan Tutkimuksen Toimikunta 252225Terveyden Tutkimuksen Toimikunta 137801Terveyden Tutkimuksen Toimikunta 218050Terveyden Tutkimuksen Toimikunta 296840
6 · The paper itself

Abstract

backgroundWound healing of retinal pigment epithelium (RPE) is a complex process that may take place in common age-related macular degeneration eye disease. The purpose of this study was to evaluate whether wounding and wound healing has an effect on Ca

methodsThe 9-day-cultured or 28-day-cultured hESC-RPEs from two different cell lines were wounded and the dynamics of spontaneous and mechanically induced intracellular Ca

resultsThe Ca

conclusionsThis acquired knowledge about Ca

Indexed as

Wound HealingCell DifferentiationHuman Embryonic Stem CellsHumansRetinal Pigment EpitheliumCa2+ wavesCell maturationhESC-RPEImage analysisMechanically induced intercellular Ca2+ wavesMechanical stimulationRPESpontaneous [Ca2+]i increasesWound healing

Identifiers

PMID30064430
PMCPMC6069779
OpenAlexW2885320156

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.