Evidence map›Paper›PMID 30064418›Full record

Trial reportBMC health services research2018

Integrating depression management into HIV primary care in central Malawi: the implementation of a pilot capacity building program.

Michael Udedi, Melissa A Stockton, Kazione Kulisewa, Mina C Hosseinipour, Bradley N Gaynes, Steven M Mphonda, Beatrice Matanje Mwagomba, Alick C Mazenga, Brian W Pence

2 registry-linked trialsOpen access · goldAbstract readClinical TrialComparative StudyMulticenter Study
In one paragraph

Trial report in BMC health services research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 48 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 3 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03555669 nacompletednot on this map

UNCPM 21609 Project SOAR Mental Health: Evaluation of the Impact of a Depression Treatment Program on Mental Health and HIV Care Outcomes in Malawi

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2017 to 2019Enrolled2,082ConditionsDepression, HIV/AIDSArmsDepression Treatment
NCT05664490 nacompletednot on this mapstarted 2023, after this paper: background citation

Youth Friendship Bench SA: Optimization of the Friendship Bench Mental Health Intervention for Adolescent Girls and Young Women in South African PrEP Delivery Settings

TypeinterventionalSponsorUniversity of California, San FranciscoRan2023 to 2024Enrolled116ConditionsDepression, Pre-Exposure ProphylaxisArmsYouth Friendship Bench SA
3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 3 syntheses or guidelines pooled it, 61 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Michael UdediNCDs & Mental Health Unit, Ministry of Health, Ministry of Health, P. O. Box 30377 Capital City, Lilongwe 3, Malawi.
Melissa A StocktonEpidemiology Department, University of North Carolina at Chapel Hill Gillings School of Global Public Health, 135 Dauer Dr, Chapel Hill, NC, 27599, USA. stocktonmelissa@gmail.com.ORCID 0000-0002-0737-7180
Kazione KulisewaMinistry of Health, Kamuzu Central Hospital and Bwaila Psychiatric Hospital, Private Bag, 149, Lilongwe, Malawi.
Mina C HosseinipourUniversity of North Carolina Project-Malawi, Tidziwe Centre, Private Bag, A-104, Lilongwe, Malawi.
Bradley N GaynesDepartment of Psychiatry, University of North Carolina at Chapel Hill School of Medicine, 333 S Columbia St, Chapel Hill, NC, 27516, USA.
Steven M MphondaUniversity of North Carolina Project-Malawi, Tidziwe Centre, Private Bag, A-104, Lilongwe, Malawi.
Beatrice Matanje MwagombaLighthouse Trust, Kamuzu Central Hospital, P.O. Box 106, Lilongwe, Malawi.
Alick C MazengaBaylor College of Medicine Abbott Fund Children's Clinical Centre of Excellence, Kamuzu Central Hospital, Private Bag, B-397, Lilongwe, Malawi.
Brian W PenceEpidemiology Department, University of North Carolina at Chapel Hill Gillings School of Global Public Health, 135 Dauer Dr, Chapel Hill, NC, 27599, USA.
University of North Carolina at Chapel Hill · USKamuzu Central Hospital · MWMinistry of Health · MWUniversity of Malawi · MW

Funding

Malawi HIV Implementation Research Scientist Training Program (MHIRST)D43TW010060 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MINA CHRISTINE HOSSEINIPOUR, Victor Mwapasa · 2015 to 2026
$3.8M
FIC NIH HHS D43 TW010060
6 · The paper itself

Abstract

backgroundIn Malawi, early retention in HIV care remains challenging. Depression is strongly associated with reduced anti-retroviral therapy (ART) adherence and viral suppression. Appropriate depression care for people initiating ART is likely to be supportive of early and continued engagement in the HIV care continuum. This paper aims to provide an overview of a task-shifting program that integrates depression screening and treatment into HIV care and the strategy used to evaluate this program, describes the implementation process, and discusses key challenges and lessons learned in the first phase of program implementation.

methodsWe are implementing a program integrating depression screening and treatment into HIV care initiation at two clinics in Lilongwe District, Malawi. The program's effect on patients' depression and HIV outcomes will be evaluated using a multiple baseline pre-post study. In this manuscript, we draw from our experiences as program implementers and some of the quantitative data to describe the process of implementation and key lessons learned.

resultsWe successfully implemented the screening phase of this program at both clinics; 88.3 and 93.2% of newly diagnosed patients have been screened for depression at each clinic respectively. 25% of enrolled patients reported symptoms of mild-to-severe depression and only 6% reported symptoms of moderate-to-severe depression. Key lessons learned from the process show the importance of utilizing existing processes and infrastructure and focusing on iterative and collaborative learning. We continued to face challenges around establishing a sense of program ownership among providers, developing capacity to diagnose and manage depression, and ensuring the availability of appropriate medication. Our efforts to address these challenges provide insight into the technical and managerial support needed to prepare for, roll out, and sustain integrated models of mental health and HIV care.

conclusionsThis activity demonstrates how a depression screening program can successfully be integrated into HIV care within the public health system in Malawi. While this program focuses on integrating depression management into HIV care, most of the lessons learned could apply to integration of mental health into any non-psychiatric specialist setting.

trial registrationClinicalTrials.gov ID [ NCT03555669 ]. Retrospectively registered on 13 June 2018.

Indexed as

Capacity BuildingDelivery of Health CareDepressive DisorderEarly DiagnosisFeasibility StudiesHIV InfectionsHumansMalawiMedication AdherencePilot ProjectsPrimary Health CarePublic HealthRetrospective StudiesDepressionHIV/AIDSImplementation scienceIntegrationMalawiMental healthService deliverySub-Saharan Africa

Identifiers

PMID30064418
PMCPMC6069990
OpenAlexW2887226488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.