ArticleBMC genomics2018
Identification of microRNAs in response to aluminum stress in the roots of Tibetan wild barley and cultivated barley.
Article in BMC genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- What Do We Know about Barley miRNAs?International journal of molecular sciences · 2022Pooled it
- Article
- Early Seedling Screening Reveals Unidentified Al Resistance Mechanisms in Lithuanian Barley Cultivars.International journal of molecular sciences · 2025Article
- miR156 Is a Negative Regulator of Aluminum Response inPlants (Basel, Switzerland) · 2025Article
- MicroRNA gatekeepers: Orchestrating rhizospheric dynamics.Journal of integrative plant biology · 2025Review
- Unveiling the role of epigenetics in leaf senescence: a comparative study to identify different epigenetic regulations of senescence types in barley leaves.BMC plant biology · 2024Article
- Site-specific analysis reveals candidate cross-kingdom small RNAs, tRNA and rRNA fragments, and signs of fungal RNA phasing in the barley-powdery mildew interaction.Molecular plant pathology · 2023Article
- Genetic portrait of polyamine transporters in barley: insights in the regulation of leaf senescence.Frontiers in plant science · 2023Article
- Nanomaterials coupled with microRNAs for alleviating plant stress: a new opening towards sustainable agriculture.Physiology and molecular biology of plants : an international journal of functional plant biology · 2022Review
- Arsenic perception and signaling: The yet unexplored world.Frontiers in plant science · 2022Review
- Identification of two chickpea multidrug and toxic compound extrusion transporter genes transcriptionally upregulated upon aluminum treatment in root tips.Frontiers in plant science · 2022Article
- Identification of microRNAs Responding to Aluminium, Cadmium and Salt Stresses in Barley Roots.Plants (Basel, Switzerland) · 2021Article
- Pi-starvation induced transcriptional changes in barley revealed by a comprehensive RNA-Seq and degradome analyses.BMC genomics · 2021Article
- Insight into the Role of Epigenetic Processes in Abiotic and Biotic Stress Response in Wheat and Barley.International journal of molecular sciences · 2020Review
- Characterization and discovery of miRNA and miRNA targets from apomictic and sexual genotypes of Eragrostis curvula.BMC genomics · 2019Article
- Molecular Mechanisms for Coping with Al Toxicity in Plants.International journal of molecular sciences · 2019Review
- Article
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Authors and funding
6 authors.
Funding
Abstract
backgroundBarley is relatively sensitive to Aluminum (Al) toxicity among cereal crops, but shows a wide genotypic difference in Al tolerance. The well-known Al-tolerant mechanism in barley is related to Al exclusion mediated by a citrate transporter HvAACT1 (Al-activated citrate transporter 1). A 1-kb insertion in the promoter region of HvAACT1 gene results in a dramatic increase of its expression level, which only occurs in some Al-tolerant cultivars. However, Al-tolerant Tibetan wild barley accession XZ29 did not have the 1-kb insertion.
resultsWe confirmed that the expression of HvAACT1 and secretion of citrate and other organic acids did not explain the difference in Al-tolerant wild barley XZ29 and Al-sensitive cultivated barley Golden Promise. To identify microRNAs (miRNAs) and their target genes responsive to Al stress in barley roots, eight small RNA libraries with two biological replicates from these two genotypes exposed to control and Al-treated conditions were constructed and submitted to deep sequencing. A total of 342 miRNAs were identified in Golden Promise and XZ29, with 296 miRNAs being commonly shared in the two genotypes. Target genes of these miRNAs were obtained through bioinformatics prediction or degradome identification. Comparative analysis detected 50 miRNAs responsive to Al stress, and some of them were found to be exclusively expressed in XZ29 and associated with Al tolerance.
conclusionsmiRNAs exclusively expressing in the wild barley were identified and found to be associated with Al stress tolerance. The current results provide a model of describing the roles of some special miRNAs associated with Al tolerance in the Tibetan wild barley.
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