ArticleBMC genomics2018
Adaptive selection of founder segments and epistatic control of plant height in the MAGIC winter wheat population WM-800.
Article in BMC genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Reverse BSA-QTLseq: A new genotype-driven bioinformatics approach for simultaneous trait mapping.Plant communications · 2026Article
- MAGIC populations: a next-generation framework for dissecting complex quantitative traits and accelerating molecular breeding in crops.Frontiers in plant science · 2026Review
- A chickpea MAGIC population to dissect the genetics of complex traits.The plant genome · 2025Article
- Recombination and structural variation in a large 8-founder wheat MAGIC population.G3 (Bethesda, Md.) · 2025Article
- Improving genomic selection in hexaploid wheat with sub-genome additive and epistatic models.G3 (Bethesda, Md.) · 2025Article
- Epistasis and pleiotropy-induced variation for plant breeding.Plant biotechnology journal · 2024Review
- Unraveling Genomic Regions Controlling Root Traits as a Function of Nitrogen Availability in the MAGIC Wheat Population WM-800.Plants (Basel, Switzerland) · 2022Article
- A Haplotype-Based GWAS Identified Trait-Improving QTL Alleles Controlling Agronomic Traits under Contrasting Nitrogen Fertilization Treatments in the MAGIC Wheat Population WM-800.Plants (Basel, Switzerland) · 2022Article
- An autoactiveProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Crafting for a better MAGIC: systematic design and test for Multiparental Advanced Generation Inter-Cross population.G3 (Bethesda, Md.) · 2021Article
- Limited haplotype diversity underlies polygenic trait architecture across 70 years of wheat breeding.Genome biology · 2021Article
- Quantitative Trait Loci Mapping of Adult Plant and Seedling Resistance to Stripe Rust (Frontiers in plant science · 2021Article
- QTL mapping of adult plant and seedling resistance to leaf rust (Puccinia triticina Eriks.) in a multiparent advanced generation intercross (MAGIC) wheat population.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Precision Mapping of a Maize MAGIC Population Identified a Candidate Gene for the Senescence-Associated Physiological Traits.Frontiers in genetics · 2021Article
- Genomic Prediction of Grain Yield in a Barley MAGIC Population Modeling Genotype per Environment Interaction.Frontiers in plant science · 2021Article
- You Had Me at "MAGIC"!: Four Barley MAGIC Populations Reveal Novel Resistance QTL for Powdery Mildew.Genes · 2020Article
- Multi-parent populations in crops: a toolbox integrating genomics and genetic mapping with breeding.Heredity · 2020Review
- Identification of modifiers of the plant height in wheat using an induced dwarf mutant controlled byPhysiology and molecular biology of plants : an international journal of functional plant biology · 2020Article
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11 authors.
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Abstract
backgroundMulti-parent advanced generation intercross (MAGIC) populations are a newly established tool to dissect quantitative traits. We developed the high resolution MAGIC wheat population WM-800, consisting of 910 F
resultsGenotyping WM-800 with 7849 SNPs revealed a low mean genetic similarity of 59.7% between MAGIC lines. WM-800 harbours distinct genomic regions exposed to segregation distortion. These are mainly located on chromosomes 2 to 6 of the wheat B genome where founder specific DNA segments were positively or negatively selected. This suggests adaptive selection of individual founder alleles during population development. The application of a genome-wide association study identified 14 quantitative trait loci (QTL) controlling plant height in WM-800, including the known semi-dwarf genes Rht-B1 and Rht-D1 and a potentially novel QTL on chromosome 5A. Additionally, epistatic effects controlled plant height. For example, two loci on chromosomes 2B and 7B gave rise to an additive epistatic effect of 13.7 cm.
conclusionThe present study demonstrates that plant height in the MAGIC-WHEAT population WM-800 is mainly determined by large-effect QTL and di-genic epistatic interactions. As a proof of concept, our study confirms that WM-800 is a valuable tool to dissect the genetic architecture of important agronomic traits.
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