Evidence map›Paper›PMID 30063766›Full record

ArticlePloS one2018

A pilot study of the Leicester ED medical infrared imaging protocol in fever and sepsis.

Timothy J Coats, Mohamed Morsy, Sana Naseer, Karoly Keresztes, Sarina Hussain, Katie Dexter, Mark R Sims

Abstract readControlled Clinical Trial
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Optical Thermography Infrastructure to Assess Thermal Distribution in Critically Ill Children.IEEE open journal of engineering in medicine and biology · 2022
    Article
  7. Review
  8. Observational
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Timothy J CoatsDepartment of Cardiovascular Sciences, Emergency Medicine Academic Group, University of Leicester, Leicester, United Kingdom.
Mohamed MorsyDepartment of Cardiovascular Sciences, Emergency Medicine Academic Group, University of Leicester, Leicester, United Kingdom.ORCID 0000-0002-1118-2263
Sana NaseerDepartment of Cardiovascular Sciences, Emergency Medicine Academic Group, University of Leicester, Leicester, United Kingdom.
Karoly KeresztesDepartment of Physics and Astronomy, University of Leicester, Leicester, United Kingdom.ORCID 0000-0002-2990-4703
Sarina HussainDepartment of Cardiovascular Sciences, Emergency Medicine Academic Group, University of Leicester, Leicester, United Kingdom.
Katie DexterDepartment of Physics and Astronomy, University of Leicester, Leicester, United Kingdom.
Mark R SimsDepartment of Physics and Astronomy, University of Leicester, Leicester, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedical Infrared Imaging (MII) is an investigative method that can be potentially used in emergency care to non-invasively detect thermal signatures associated with change in blood flow. We have developed a protocol for the use of MII in the Emergency Department (ED) and shown that it is feasible. To derive initial data for sample size calculations, we performed an exploratory study in patients with fever and sepsis.

methodsThe Leicester MII protocol was used to image the temperature patterns along the arm among three patient groups (control, fever and sepsis) of a total 56 patients. Anatomical markers were used to divide this gradient into upper arm, forearm, hand and finger regions. Variations in measurements within and between these regions were described.

resultsThe thermal gradient down the arm was successfully extracted in all patients. The distribution of values in each region of the arm was described in control, fever and sepsis patients. There was a significant gradient between upper arm and finger in controls (2.75, p < 0.0001), but no gradient in fever (p = 0.944) or sepsis (p = 0.710). This was reflected in the finger/arm difference, which was of -2.74°C (±3.50) in controls, -0.39C (±2.48) in fever, and -1.80°C (±3.09) in sepsis.

conclusionsThis study found different thermal gradients along the arm in control and febrile groups, and defined the degree of individual variation. It is likely that the difference between upper arm temperature and finger temperature (representing the temperature gradient down the arm) may be more useful than absolute measurements in future studies.

Indexed as

Infrared RaysAdolescentAdultAgedArmBody TemperatureChildChild, PreschoolClinical ProtocolsDiagnostic ImagingEmergency Service, HospitalFeasibility StudiesFemaleFeverFingersForearm

Identifiers

PMID30063766
PMCPMC6067732

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.