ArticlePloS one2018
Oat beta-glucan as a dietary supplement for dogs.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 39 citations in OpenAlex.
- Response of gut microbiome and metabolomic profiles to POLYCAN, a β-glucan derived from Aureobasidium pullulans SM-2001 in beagles.Journal of animal science and biotechnology · 2026Article
- From functional ingredients to bioactive compounds: a review of their role in commercial pet food.Veterinary research communications · 2026Review
- Metabolic and hormonal effects of whole grains of rye, oats and wheat in dog food.Journal of animal science · 2026Article
- Effects of Dietary Supplementation with Whole Lamb Omasum on Gut Health and Metabolism in Shiba Inu Dogs.Veterinary sciences · 2026Article
- Effects of a single-cell protein source fromFrontiers in veterinary science · 2026Article
- Nutraceuticals, Social Interaction, and Psychophysiological Influence on Pet Health and Well-Being: Focus on Dogs and Cats.Veterinary sciences · 2025Review
- Serum Metabolomic Profiling in Healthy Dogs Supplemented with Increasing Levels of Purified Beta-1,3/1,6-Glucans.Animals : an open access journal from MDPI · 2025Article
- Enhancing Pacific white shrimp immunity againstVeterinary world · 2025Article
- Effects of L-β-Galactoglucan Supplementation on Growth Performance, Palatability, and Intestinal Microbiota in Adult Beagle Dogs.Metabolites · 2025Article
- Effects of feedingFrontiers in veterinary science · 2025Article
- The Impact of Fiber Source on Digestive Function, Fecal Microbiota, and Immune Response in Adult Dogs.Animals : an open access journal from MDPI · 2024Article
- β-glucans from Euglena gracilis or Saccharomyces cerevisiae effects on immunity and inflammatory parameters in dogs.PloS one · 2024Article
- The effect of puppyhood and adolescent diet on the incidence of chronic enteropathy in dogs later in life.Scientific reports · 2023Article
- Effect of diet on postprandial glycemic and insulin responses in healthy dogs.Frontiers in veterinary science · 2023Article
- Metabolic variables of obese dogs with insulin resistance supplemented with yeast beta-glucan.BMC veterinary research · 2022Article
- Evaluation of Fermented Oat and Black Soldier Fly Larva as Food Ingredients in Senior Dog Diets.Animals : an open access journal from MDPI · 2021Article
- Puppyhood diet as a factor in the development of owner-reported allergy/atopy skin signs in adult dogs in Finland.Journal of veterinary internal medicine · 2021Article
- Supplemental Fiber Affects Body Temperature and Fecal Metabolites but Not Respiratory Rate or Body Composition in Mid-Distance Training Sled Dogs.Frontiers in veterinary science · 2021Article
- Dietary supplementation of beta-glucan-rich molasses yeast powder on antibody response to swine fever virus and hematology of starter-grower pigs.Tropical animal health and production · 2020Article
- Effect of Added Dietary Betaine and Soluble Fiber on Metabolites and Fecal Microbiome in Dogs with Early Renal Disease.Metabolites · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to evaluate the effects of oat beta-glucan supplementation on metabolic, physiological, immunological and nutritional variables in adult dogs. Fourteen dogs were fed a control diet or a diet supplemented with 1% beta-glucan during 71 days. Serum concentrations of glucose, total cholesterol and lipoprotein fractions, as well as plasma concentrations of peptide YY and ghrelin, were determined. In addition, coefficient of total tract apparent macronutrient digestibility (CTTAD), food intake and fecal output, score, and pH were evaluated. For evaluation of immunological variables, serum concentrations of interleukin-4 and interferon gamma were determined on days 0, 57 and 71, which corresponded to blood collection prior to beta-glucan supplementation, and at 7 and 14 days post first and second dose of vaccination (Pneumodog®, Merial, Campinas, Brazil), respectively. Animals fed the supplemented diet showed (P<0.05) lower serum concentrations of total cholesterol and low and very low density lipoproteins, lower coefficients of total tract apparent digestibility of dry matter, organic matter, mineral matter and ether extract, higher fecal output and lower fecal consistency, as well as a tendency (P = 0.07) of decreasing the coefficient of total tract apparent digestibility of crude protein. Moreover, the supplemented diet resulted in lower number of red blood cells, hematocrit percentage and hemoglobin concentration 21 days post-vaccination as well as lower serum concentration of interleukin-4 seven days post-vaccination (P<0.05). It is concluded that oat beta-glucan extract can be used as a dietary supplement for dogs at a dose of 10 g/kg of food, being effective in reducing blood concentrations of total cholesterol, LDL-c and VLDL-c as well as CTTAD of nutrients, demonstrating a potential to be used in the feeding of obese animals. In addition, by reducing the predominance of a Th2 response, oat beta-glucan can positively modulate the vaccine response of animals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.