ArticlePLoS biology2018
Comparative genomics and the nature of placozoan species.
Article in PLoS biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed.
- Retinoid-X receptor action and disruption in development.Developmental biology · 2026Review
- Cosmopolitan Gene Families With Known Functions Are Hotspots for the Evolution of Novel Genes in Stony Corals.Genome biology and evolution · 2026Article
- Establishment of a transgenic protocol inZoological research · 2026Article
- Early transitions in the evolution of cognition.History and philosophy of the life sciences · 2025Article
- Evolution of iGluR ligand specificity, polyamine regulation, and ion selectivity inferred from a placozoan epsilon receptor.Communications biology · 2025Article
- Placozoan secretory cell types implicated in feeding, innate immunity and regulation of behavior.PloS one · 2025Article
- Tolerance of Placozoa for temperate climates: Evidence for known and new placozoan clades in the southern waters of Australia.PloS one · 2025Article
- Mint/X11 PDZ domains from non-bilaterian animals recognize and bind CaScientific reports · 2024Article
- Beauty in the beast - Placozoan biodiversity explored through molluscan predator genomics.Ecology and evolution · 2024Article
- The placozoan Trichoplax.Nature methods · 2024Article
- Brief History of Placozoa.Methods in molecular biology (Clifton, N.J.) · 2024Review
- Long-Term Culturing of Placozoans (Trichoplax and Hoilungia).Methods in molecular biology (Clifton, N.J.) · 2024Article
- Bioinformatic Prohormone Discovery in Basal Metazoans: Insights from Trichoplax.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Article
- On the origin of appetite: GLWamide in jellyfish represents an ancestral satiety neuropeptide.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Transposon-derived transcription factors across metazoans.Frontiers in cell and developmental biology · 2023Article
- Deeply conserved synteny and the evolution of metazoan chromosomes.Science advances · 2022Article
- Actinoporin-like Proteins Are Widely Distributed in the Phylum Porifera.Marine drugs · 2022Article
- Studying Placozoa WBR in the Simplest Metazoan Animal, Trichoplax adhaerens.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Expanding of Life Strategies in Placozoa: Insights From Long-Term Culturing ofFrontiers in cell and developmental biology · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Placozoans are a phylum of nonbilaterian marine animals currently represented by a single described species, Trichoplax adhaerens, Schulze 1883. Placozoans arguably show the simplest animal morphology, which is identical among isolates collected worldwide, despite an apparently sizeable genetic diversity within the phylum. Here, we use a comparative genomics approach for a deeper appreciation of the structure and causes of the deeply diverging lineages in the Placozoa. We generated a high-quality draft genome of the genetic lineage H13 isolated from Hong Kong and compared it to the distantly related T. adhaerens. We uncovered substantial structural differences between the two genomes that point to a deep genomic separation and provide support that adaptation by gene duplication is likely a crucial mechanism in placozoan speciation. We further provide genetic evidence for reproductively isolated species and suggest a genus-level difference of H13 to T. adhaerens, justifying the designation of H13 as a new species, Hoilungia hongkongensis nov. gen., nov. spec., now the second described placozoan species and the first in a new genus. Our multilevel comparative genomics approach is, therefore, likely to prove valuable for species distinctions in other cryptic microscopic animal groups that lack diagnostic morphological characters, such as some nematodes, copepods, rotifers, or mites.
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