Evidence map›Paper›PMID 30063192›Full record

ArticleRadiology2018

Robust Motion Correction Strategy for Structural MRI in Unsedated Children Demonstrated with Three-dimensional Radial MPnRAGE.

Steven Kecskemeti, Alexey Samsonov, Julia Velikina, Aaron S Field, Patrick Turski, Howard Rowley, Janet E Lainhart, Andrew L Alexander

Abstract read
In one paragraph

Article in Radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  19. Free-breathing, fat-corrected TMagnetic resonance in medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Steven KecskemetiFrom the Waisman Center (S.K., J.E.L., A.L.A.) and Departments of Radiology (S.K., A.S., A.S.F., P.T., H.R.), Medical Physics (J.V., A.L.A.), and Psychiatry (J.E.L., A.L.A.), University of Wisconsin-Madison, T123 Waisman Center, 1500 Highland Ave, Madison, WI 53705.ORCID 0000-0003-3589-430X
Alexey SamsonovFrom the Waisman Center (S.K., J.E.L., A.L.A.) and Departments of Radiology (S.K., A.S., A.S.F., P.T., H.R.), Medical Physics (J.V., A.L.A.), and Psychiatry (J.E.L., A.L.A.), University of Wisconsin-Madison, T123 Waisman Center, 1500 Highland Ave, Madison, WI 53705.
Julia VelikinaFrom the Waisman Center (S.K., J.E.L., A.L.A.) and Departments of Radiology (S.K., A.S., A.S.F., P.T., H.R.), Medical Physics (J.V., A.L.A.), and Psychiatry (J.E.L., A.L.A.), University of Wisconsin-Madison, T123 Waisman Center, 1500 Highland Ave, Madison, WI 53705.
Aaron S FieldFrom the Waisman Center (S.K., J.E.L., A.L.A.) and Departments of Radiology (S.K., A.S., A.S.F., P.T., H.R.), Medical Physics (J.V., A.L.A.), and Psychiatry (J.E.L., A.L.A.), University of Wisconsin-Madison, T123 Waisman Center, 1500 Highland Ave, Madison, WI 53705.
Patrick TurskiFrom the Waisman Center (S.K., J.E.L., A.L.A.) and Departments of Radiology (S.K., A.S., A.S.F., P.T., H.R.), Medical Physics (J.V., A.L.A.), and Psychiatry (J.E.L., A.L.A.), University of Wisconsin-Madison, T123 Waisman Center, 1500 Highland Ave, Madison, WI 53705.
Howard RowleyFrom the Waisman Center (S.K., J.E.L., A.L.A.) and Departments of Radiology (S.K., A.S., A.S.F., P.T., H.R.), Medical Physics (J.V., A.L.A.), and Psychiatry (J.E.L., A.L.A.), University of Wisconsin-Madison, T123 Waisman Center, 1500 Highland Ave, Madison, WI 53705.
Janet E LainhartFrom the Waisman Center (S.K., J.E.L., A.L.A.) and Departments of Radiology (S.K., A.S., A.S.F., P.T., H.R.), Medical Physics (J.V., A.L.A.), and Psychiatry (J.E.L., A.L.A.), University of Wisconsin-Madison, T123 Waisman Center, 1500 Highland Ave, Madison, WI 53705.
Andrew L AlexanderFrom the Waisman Center (S.K., J.E.L., A.L.A.) and Departments of Radiology (S.K., A.S., A.S.F., P.T., H.R.), Medical Physics (J.V., A.L.A.), and Psychiatry (J.E.L., A.L.A.), University of Wisconsin-Madison, T123 Waisman Center, 1500 Highland Ave, Madison, WI 53705.

Funding

Summer Research ExperienceP50MH100031 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI KALIN, NED H · 2013 to 2017
$10.4M
Waisman Intellectual and Developmental Disabilities Research Center Down Syndrome RegistryU54HD090256 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI POLLAK, SETH D · 2016 to 2020
$6.0M
Alzheimer's Disease Connectome ProjectUF1AG051216 · NIA · MEDICAL COLLEGE OF WISCONSIN · PI BENDLIN, BARBARA BRIGITTA, LI, SHI-JIANG · 2016 to 2019
$5.8M
Biological Determinants of Brain Variation in AutismR01MH097464 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI LAINHART, JANET ELIZABETH, LANGE, NICHOLAS T · 2013 to 2017
$2.9M
Advanced Perfusion MRI of Treatment Response and Progression in GlioblastomaR21EB018483 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI SAMSONOV, ALEXEY · 2014 to 2015
$421k
A Neuroimaging Framework for Detection of NeuroplasticityR21NS091733 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI ALEXANDER, ANDREW L, GREEN, CHRISTOPHER S · 2015 to 2016
$421k
Technologies for Improved Quantitative Relaxometry in Awake ChildrenR21HD078119 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI ALEXANDER, ANDREW L · 2014 to 2015
$401k
NIA NIH HHS UF1 AG051216NIBIB NIH HHS R21 EB018483NICHD NIH HHS R21 HD078119NICHD NIH HHS U54 HD090256NIMH NIH HHS P50 MH100031NIMH NIH HHS R01 MH097464NINDS NIH HHS R21 NS091733
6 · The paper itself

Abstract

Purpose To develop and evaluate a retrospective method to minimize motion artifacts in structural MRI. Materials and Methods The motion-correction strategy was developed for three-dimensional radial data collection and demonstrated with MPnRAGE, a technique that acquires high-resolution volumetric magnetization-prepared rapid gradient-echo, or MPRAGE, images with multiple tissue contrasts. Forty-four pediatric participants (32 with autism spectrum disorder [mean age ± standard deviation, 13 years ± 3] and 12 age-matched control participants [mean age, 12 years ± 3]) were imaged without sedation. Images with and images without retrospective motion correction were scored by using a Likert scale (0-4 for unusable to excellent) by two experienced neuroradiologists. The Tenengrad metric (a reference-free measure of image sharpness) and statistical analyses were performed to determine the effects of performing retrospective motion correction. Results MPnRAGE T1-weighted images with retrospective motion correction were all judged to have good or excellent quality. In some cases, retrospective motion correction improved the image quality from unusable (Likert score of 0) to good (Likert score of 3). Overall, motion correction improved mean Likert scores from 3.0 to 3.8 and reduced standard deviations from 1.1 to 0.4. Image quality was significantly improved with motion correction (Mann-Whitney U test; P < .001). Intraclass correlation coefficients for absolute agreement of Tenengrad scores with reviewers 1 and 2 were 0.92 and 0.88 (P < .0005 for both), respectively. In no cases did the retrospective motion correction induce severe image degradation. Conclusion Retrospective motion correction of MPnRAGE data were shown to be highly effective for consistently improving image quality of T1-weighted MRI in unsedated pediatric participants, while also enabling multiple tissue contrasts to be reconstructed for structural analysis. © RSNA, 2018 Online supplemental material is available for this article.

Indexed as

ArtifactsAutism Spectrum DisorderAdolescentBrainChildFemaleHumansImage Interpretation, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingMaleMotionNeuroimagingReproducibility of ResultsRetrospective Studies

Identifiers

PMID30063192
PMCPMC6192848

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