Evidence map›Paper›PMID 30063172›Full record

ArticleRadiology2018

MRI-defined White Matter Microstructural Alteration Associated with Soccer Heading Is More Extensive in Women than Men.

Todd G Rubin, Eva Catenaccio, Roman Fleysher, Liane E Hunter, Naomi Lubin, Walter F Stewart, Mimi Kim, Richard B Lipton, Michael L Lipton

Abstract read
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In one paragraph

Article in Radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
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  17. Concussion in Female Athletes of Contact Sports: A Scoping Review.Orthopaedic journal of sports medicine · 2024
    Article
  18. Article
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  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Todd G RubinFrom the Gruss Magnetic Resonance Research Center, Department of Radiology (T.G.R., R.F., L.E.H., N.L., M.L.L.), Departments of Epidemiology and Population Health (M.K., R.B.L.), Neurology (R.B.L.), and Psychiatry and Behavioral Sciences (M.L.L.), and the Dominick P. Purpura Department of Neuroscience (T.G.R., M.L.L.), Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461; Departments of Radiology (M.L.L.) and Neurology (R.B.L.), Montefiore Medical Center, Bronx, NY; Department of Pediatrics, Johns Hopkins University, Baltimore, Md (E.C.); and Sutter Health, Walnut Creek, Calif (W.F.S.).ORCID 0000-0002-2821-5877
Eva CatenaccioFrom the Gruss Magnetic Resonance Research Center, Department of Radiology (T.G.R., R.F., L.E.H., N.L., M.L.L.), Departments of Epidemiology and Population Health (M.K., R.B.L.), Neurology (R.B.L.), and Psychiatry and Behavioral Sciences (M.L.L.), and the Dominick P. Purpura Department of Neuroscience (T.G.R., M.L.L.), Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461; Departments of Radiology (M.L.L.) and Neurology (R.B.L.), Montefiore Medical Center, Bronx, NY; Department of Pediatrics, Johns Hopkins University, Baltimore, Md (E.C.); and Sutter Health, Walnut Creek, Calif (W.F.S.).
Roman FleysherFrom the Gruss Magnetic Resonance Research Center, Department of Radiology (T.G.R., R.F., L.E.H., N.L., M.L.L.), Departments of Epidemiology and Population Health (M.K., R.B.L.), Neurology (R.B.L.), and Psychiatry and Behavioral Sciences (M.L.L.), and the Dominick P. Purpura Department of Neuroscience (T.G.R., M.L.L.), Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461; Departments of Radiology (M.L.L.) and Neurology (R.B.L.), Montefiore Medical Center, Bronx, NY; Department of Pediatrics, Johns Hopkins University, Baltimore, Md (E.C.); and Sutter Health, Walnut Creek, Calif (W.F.S.).
Liane E HunterFrom the Gruss Magnetic Resonance Research Center, Department of Radiology (T.G.R., R.F., L.E.H., N.L., M.L.L.), Departments of Epidemiology and Population Health (M.K., R.B.L.), Neurology (R.B.L.), and Psychiatry and Behavioral Sciences (M.L.L.), and the Dominick P. Purpura Department of Neuroscience (T.G.R., M.L.L.), Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461; Departments of Radiology (M.L.L.) and Neurology (R.B.L.), Montefiore Medical Center, Bronx, NY; Department of Pediatrics, Johns Hopkins University, Baltimore, Md (E.C.); and Sutter Health, Walnut Creek, Calif (W.F.S.).ORCID 0000-0002-3464-1549
Naomi LubinFrom the Gruss Magnetic Resonance Research Center, Department of Radiology (T.G.R., R.F., L.E.H., N.L., M.L.L.), Departments of Epidemiology and Population Health (M.K., R.B.L.), Neurology (R.B.L.), and Psychiatry and Behavioral Sciences (M.L.L.), and the Dominick P. Purpura Department of Neuroscience (T.G.R., M.L.L.), Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461; Departments of Radiology (M.L.L.) and Neurology (R.B.L.), Montefiore Medical Center, Bronx, NY; Department of Pediatrics, Johns Hopkins University, Baltimore, Md (E.C.); and Sutter Health, Walnut Creek, Calif (W.F.S.).
Walter F StewartFrom the Gruss Magnetic Resonance Research Center, Department of Radiology (T.G.R., R.F., L.E.H., N.L., M.L.L.), Departments of Epidemiology and Population Health (M.K., R.B.L.), Neurology (R.B.L.), and Psychiatry and Behavioral Sciences (M.L.L.), and the Dominick P. Purpura Department of Neuroscience (T.G.R., M.L.L.), Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461; Departments of Radiology (M.L.L.) and Neurology (R.B.L.), Montefiore Medical Center, Bronx, NY; Department of Pediatrics, Johns Hopkins University, Baltimore, Md (E.C.); and Sutter Health, Walnut Creek, Calif (W.F.S.).
Mimi KimFrom the Gruss Magnetic Resonance Research Center, Department of Radiology (T.G.R., R.F., L.E.H., N.L., M.L.L.), Departments of Epidemiology and Population Health (M.K., R.B.L.), Neurology (R.B.L.), and Psychiatry and Behavioral Sciences (M.L.L.), and the Dominick P. Purpura Department of Neuroscience (T.G.R., M.L.L.), Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461; Departments of Radiology (M.L.L.) and Neurology (R.B.L.), Montefiore Medical Center, Bronx, NY; Department of Pediatrics, Johns Hopkins University, Baltimore, Md (E.C.); and Sutter Health, Walnut Creek, Calif (W.F.S.).
Richard B LiptonFrom the Gruss Magnetic Resonance Research Center, Department of Radiology (T.G.R., R.F., L.E.H., N.L., M.L.L.), Departments of Epidemiology and Population Health (M.K., R.B.L.), Neurology (R.B.L.), and Psychiatry and Behavioral Sciences (M.L.L.), and the Dominick P. Purpura Department of Neuroscience (T.G.R., M.L.L.), Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461; Departments of Radiology (M.L.L.) and Neurology (R.B.L.), Montefiore Medical Center, Bronx, NY; Department of Pediatrics, Johns Hopkins University, Baltimore, Md (E.C.); and Sutter Health, Walnut Creek, Calif (W.F.S.).
Michael L LiptonFrom the Gruss Magnetic Resonance Research Center, Department of Radiology (T.G.R., R.F., L.E.H., N.L., M.L.L.), Departments of Epidemiology and Population Health (M.K., R.B.L.), Neurology (R.B.L.), and Psychiatry and Behavioral Sciences (M.L.L.), and the Dominick P. Purpura Department of Neuroscience (T.G.R., M.L.L.), Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, NY 10461; Departments of Radiology (M.L.L.) and Neurology (R.B.L.), Montefiore Medical Center, Bronx, NY; Department of Pediatrics, Johns Hopkins University, Baltimore, Md (E.C.); and Sutter Health, Walnut Creek, Calif (W.F.S.).

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007288 · NIGMS · YESHIVA UNIVERSITY · PI AKABAS, MYLES H. · 1985 to 2022
$35.6M
Brain injury due to soccer heading and opportunities for its mitigationR01NS082432 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI LIPTON, MICHAEL LAWRENCE · 2013 to 2017
$3.5M
NIGMS NIH HHS T32 GM007288NINDS NIH HHS R01 NS082432
6 · The paper itself

Abstract

Purpose To examine the role of sex in abnormal white matter microstructure after soccer heading as identified by using the diffusion-tensor imaging (DTI) metric fractional anisotropy (FA). Materials and Methods In this prospective cross-sectional study, 98 individuals who were enrolled in a larger prospective study of amateur soccer players (from 2013 to 2016) were matched 1:1 for age and history of soccer heading in the prior 12 months. Among the subjects, 49 men (mean age, 25.7 years; range, 18-50 years) and 49 women (mean age, 25.8 years; range, 18-50 years) with median total soccer headings per year of 487 and 469, respectively, underwent 3.0-T DTI. Images were registered to the Johns Hopkins University template. A voxelwise linear regression was fitted for FA with terms for the number of headings during the previous 12 months and its interaction with sex after controlling for the following potential confounders: age, years of education, number of lifetime concussions, and handedness. In the resulting statistical maps, P < .01 indicated a statistically significant difference, with a threshold cluster size larger than 100 mm

Indexed as

AthletesSoccerAdolescentAdultAnisotropyCross-Sectional StudiesDiffusion Tensor ImagingFemaleHumansLongitudinal StudiesMagnetic Resonance ImagingMaleMiddle AgedNeuroimagingProspective StudiesSex Factors

Identifiers

PMID30063172
PMCPMC6209057

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.