Evidence map›Paper›PMID 30062787›Full record

ArticleExperimental physiology2018

Type 2 diabetes and older age contribute to elevated plasma microparticle concentrations independent of chronic stroke.

Rian Q Landers-Ramos, Monica C Serra, Jacob B Blumenthal, Alice S Ryan, Charlene E Hafer-Macko, Steven J Prior

Open access · bronzeAbstract read
In one paragraph

Article in Experimental physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Rian Q Landers-RamosDivision of Gerontology and Geriatric Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Monica C SerraDivision of Gerontology and Geriatric Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Jacob B BlumenthalDivision of Gerontology and Geriatric Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Alice S RyanDivision of Gerontology and Geriatric Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Charlene E Hafer-MackoDivision of Gerontology and Geriatric Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Steven J PriorDivision of Gerontology and Geriatric Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
University of Maryland, Baltimore · USGeriatric Research Education and Clinical Center · USUniversity of Maryland, College Park · US

Funding

University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI Stephen L. Seliger · 2006 to 2026
$28.9M
Vascular Biology Training ProgramT32HL007698 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI Rosemary A Kozar, Dudley K. Strickland · 1991 to 2026
$8.7M
Aging, Inflammation and Exercise in Chronic StrokeR01AG030075 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI HAFER-MACKO, CHARLENE E, RYAN, ALICE S. · 2008 to 2012
$2.4M
Effects of Aerobic Exerise on EPCs and Vascular Dysfunction in Aging and T2DMK23AG040775 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI PRIOR, STEVEN J · 2012 to 2014
$532k
Exercise training, CACs, and vascular function in older veterans with IGTI01CX000730 · VA · BALTIMORE VA MEDICAL CENTER · PI PRIOR, STEVEN J · 2014 to 2017
–
Aerobic Training to Improve Energy Utilization and Antioxidant Capacity in StrokeIK2RX000944 · VA · VETERANS HEALTH ADMINISTRATION · PI SERRA, MONICA C · 2014 to 2019
–
CSRD VA I01 CX000730NHLBI NIH HHS T32 HL007698NIA NIH HHS K23 AG040775NIA NIH HHS P30 AG028747NIA NIH HHS R01 AG030075NIH HHS K23-AG040775NIH HHS R01-AG030075RRD VA IK2 RX000944
6 · The paper itself

Abstract

NEW

findingsWhat is the central question of this study? What is the effect of chronic stroke on circulating microparticle populations, accounting for potential effects of age and type 2 diabetes? What is the main finding and its importance? Elevated concentrations of CD31 ABSTRACT: The elevated circulating concentration of endothelial microparticles (MPs) may provide an index of the extent and nature of cellular damage in chronic stroke. The purpose of this study was to determine the circulating concentrations of CD31

Indexed as

AdolescentAdultAgedAge FactorsCell-Derived MicroparticlesDiabetes Mellitus, Type 2FemaleHumansMaleMiddle AgedOxygen ConsumptionRisk FactorsStrokeYoung Adultdiabetes mellitusendothelial microparticleolder agestroke

Identifiers

PMID30062787
PMCPMC6449859
OpenAlexW2886557719

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.