Evidence map›Paper›PMID 30062599›Full record

ArticleIntensive care medicine experimental2018

Evaluation of end-tidal carbon dioxide gradient as a predictor of volume responsiveness in spontaneously breathing healthy adults.

María C Arango-Granados, Virginia Zarama Córdoba, Andrés M Castro Llanos, Luis A Bustamante Cristancho

Registry-linked trialAbstract read
In one paragraph

Article in Intensive care medicine experimental, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05557461 (Assessment of Fluid Responsiveness in Septic Shock Patients, Can End-tidal co2 Measurement Help?, a Prospective Observational Study), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05557461 unknown statusnot on this mapstarted 2022, after this paper: background citation

Assessment of Fluid Responsiveness in Septic Shock Patients, Can End-tidal co2 Measurement Help?, a Prospective Observational Study

TypeobservationalSponsorBozyaka Training and Research HospitalRan2022 to 2023Enrolled60ConditionsSeptic Shock, Hypovolemia, SepsisArmsEnd-tifdal co2, systolic, diastolic blood pressure, ppv values and vci distensibility
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

María C Arango-GranadosUniversidad Icesi, Calle 18 No. 122-135 Pance, Cali, Colombia. arango.mc@gmail.com.ORCID http://orcid.org/0000-0003-3494-0810
Virginia Zarama CórdobaFundación Valle del Lili, Av. Simón Bolívar. Cra 98 # 18-49, Cali, Colombia.
Andrés M Castro LlanosFundación Valle del Lili, Av. Simón Bolívar. Cra 98 # 18-49, Cali, Colombia.
Luis A Bustamante CristanchoFundación Valle del Lili, Av. Simón Bolívar. Cra 98 # 18-49, Cali, Colombia.

Funding

Fundación Valle del Lili NA
6 · The paper itself

Abstract

backgroundMethods to guide fluid therapy in spontaneously breathing patients are scarce. No studies have reported the accuracy of end-tidal CO

methodsWe conducted a prospective study in healthy adult human volunteers. A PLR maneuver was performed and cardiac output (CO) was measured by transthoracic echocardiography. ET-CO2 was measured with non-invasive capnographs. Volume responsiveness was defined as an increase in cardiac output (CO) > 12% at 90 s after PLR.

resultsOf the 50 volunteers, 32% were classified as volume responders. In this group, the left ventricle outflow tract velocity time integral (VTI

conclusionsΔET-CO

Indexed as

Blood volume determinationCapnographyCardiac outputDoppler echocardiographyHemodynamic monitoring

Identifiers

PMID30062599
PMCPMC6066588

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.