Evidence map›Paper›PMID 30062428›Full record

ArticleCellular and molecular life sciences : CMLS2018

Crosstalk between FGF23- and angiotensin II-mediated Ca

Ketaki N Mhatre, Paulina Wakula, Oliver Klein, Egbert Bisping, Jakob Völkl, Burkert Pieske, Frank R Heinzel

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular life sciences : CMLS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Iron deficiency after kidney transplantation.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021
    Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ketaki N MhatreDepartment of Internal Medicine and Cardiology, Charité University Medicine, Campus Virchow-Klinikum, 13353, Berlin, Germany.
Paulina WakulaDepartment of Internal Medicine and Cardiology, Charité University Medicine, Campus Virchow-Klinikum, 13353, Berlin, Germany.
Oliver KleinDepartment of Internal Medicine and Cardiology, Charité University Medicine, Campus Virchow-Klinikum, 13353, Berlin, Germany.
Egbert BispingDepartment of Cardiology, Medical University Graz, Auenbruggerplatz 15, 8036, Graz, Austria.
Jakob VölklDepartment of Internal Medicine and Cardiology, Charité University Medicine, Campus Virchow-Klinikum, 13353, Berlin, Germany.
Burkert PieskeDepartment of Internal Medicine and Cardiology, Charité University Medicine, Campus Virchow-Klinikum, 13353, Berlin, Germany.
Frank R HeinzelDepartment of Internal Medicine and Cardiology, Charité University Medicine, Campus Virchow-Klinikum, 13353, Berlin, Germany. frank.heinzel@charite.de.
Charité - Universitätsmedizin Berlin · DEGerman Centre for Cardiovascular Research · DEMedical University of Graz · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart failure (HF) manifestation and progression are driven by systemic activation of neuroendocrine signaling cascades, such as the renin-angiotensin aldosterone system (RAAS). Fibroblast growth factor 23 (FGF23), an endocrine hormone, is linked to HF and cardiovascular mortality. It is also a mediator of left-ventricular hypertrophy (LVH). In vivo, high circulating levels of FGF23 are associated with an altered systemic RAAS response. FGF23 is proposed to trigger pathological signaling mediated by Ca

Indexed as

Angiotensin IIAnimalsAnimals, NewbornCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2Calcium SignalingCardiomegalyCells, CulturedFibroblast Growth Factor-23Fibroblast Growth FactorsGene ExpressionHistone DeacetylasesMyocytes, CardiacRatsReceptor, Angiotensin, Type 1Angiotensin IICalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2Fgf23 protein, mouseFibroblast Growth Factor-23Fibroblast Growth FactorsHdac5 protein, mouseHistone DeacetylasesReceptor, Angiotensin, Type 1AutocrineCardio-renal axisLocal renin-angiotensin systemNuclear Ca2+ signalingVentricle cardiomyocytes

Identifiers

PMID30062428
PMCPMC11105615
OpenAlexW2885192146

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.