Evidence map›Paper›PMID 30062167›Full record

ArticleJACC. Basic to translational science2017

Dietary Fat, Sugar Consumption, and Cardiorespiratory Fitness in Patients With Heart Failure With Preserved Ejection Fraction.

Salvatore Carbone, Justin M Canada, Leo F Buckley, Cory R Trankle, Hayley E Billingsley, Dave L Dixon, Adolfo G Mauro, Sofanit Dessie, Dinesh Kadariya, Eleonora Mezzaroma and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Basic to translational science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

  1. Pooled it
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  13. The treatment of chronic anemia in heart failure: a global approach.Clinical research in cardiology : official journal of the German Cardiac Society · 2024
    Review
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  15. Article
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  18. Article
  19. Deranged Myocardial Fatty Acid Metabolism in Heart Failure.International journal of molecular sciences · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Salvatore CarboneVCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia.
Justin M CanadaVCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia.
Leo F BuckleyDepartment of Pharmacotherapy and Outcome Sciences, Virginia Commonwealth University, Richmond, Virginia.
Cory R TrankleVCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia.
Hayley E BillingsleyVCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia.
Dave L DixonDepartment of Pharmacotherapy and Outcome Sciences, Virginia Commonwealth University, Richmond, Virginia.
Adolfo G MauroVCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia.
Sofanit DessieVCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia.
Dinesh KadariyaVCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia.
Eleonora MezzaromaDepartment of Pharmacotherapy and Outcome Sciences, Virginia Commonwealth University, Richmond, Virginia.
Raffaella BuzzettiDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Ross ArenaDepartment of Physical Therapy, College of Applied Health Sciences, University of Illinois, Chicago, Illinois.
Benjamin W Van TassellDepartment of Pharmacotherapy and Outcome Sciences, Virginia Commonwealth University, Richmond, Virginia.
Stefano ToldoVCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia.
Antonio AbbateVCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia.
Virginia Commonwealth University · USSapienza University of Rome · ITUniversity of Illinois Urbana-Champaign · US

Funding

Center for Clinical and Translational ResearchUL1TR000058 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2012 to 2015
$12.5M
Interleukin-1 blockade in heart failure with preserved ejection fractionR34HL118348 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI ABBATE, ANTONIO, VAN TASSELL, BENJAMIN W · 2014 to 2015
$681k
NCATS NIH HHS UL1 TR000058NHLBI NIH HHS R34 HL118348
6 · The paper itself

Abstract

Heart failure with preserved ejection fraction (HFpEF) is associated with obesity and, indirectly, with unhealthy diet. The role of dietary components in HFpEF is, however, largely unknown. In this study, the authors showed that in obese HFpEF patients, consumption of unsaturated fatty acids (UFA), was associated with better cardiorespiratory fitness, and UFA consumption correlated with better diastolic function and with greater fat-free mass. Similarly, mice fed with a high-fat diet rich in UFA and low in sugars had preserved myocardial function and reduced weight gain. Randomized clinical trials increasing dietary UFA consumption and reducing sugar consumption are warranted to confirm and expand our findings.

Indexed as

body compositionCPX, cardiopulmonary exercise testingCRF, cardiorespiratory fitnessCV, cardiovasculardietDT, deceleration timeFFM, fat-free massFM, fat massheart failure with preserved ejection fractionHF, heart failureHFpEF, heart failure with preserved ejection fractionIQR, interquartile rangeMUFA, monounsaturated fatty acidobesityPUFA, polyunsaturated fatty acidSFA, saturated fatty acidUFA, unsaturated fatty acidunsaturated fatty acidsVo2, oxygen consumption

Identifiers

PMID30062167
PMCPMC6058958
OpenAlexW2766174328

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.