Evidence map›Paper›PMID 30062119›Full record

ArticleACS central science2018

A Universal Biomolecular Concentrator To Enhance Biomolecular Surface Binding Based on Acoustic NEMS Resonator.

Wenpeng Liu, Shuting Pan, Hongxiang Zhang, Zifan Tang, Ji Liang, Yanyan Wang, Menglun Zhang, Xiaodong Hu, Wei Pang, Xuexin Duan

Abstract read
In one paragraph

Article in ACS central science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wenpeng LiuState Key Laboratory of Precision Measuring Technology & Instruments, Tianjin University, Tianjin 300072, China.
Shuting PanState Key Laboratory of Precision Measuring Technology & Instruments, Tianjin University, Tianjin 300072, China.
Hongxiang ZhangState Key Laboratory of Precision Measuring Technology & Instruments, Tianjin University, Tianjin 300072, China.
Zifan TangState Key Laboratory of Precision Measuring Technology & Instruments, Tianjin University, Tianjin 300072, China.
Ji LiangState Key Laboratory of Precision Measuring Technology & Instruments, Tianjin University, Tianjin 300072, China.
Yanyan WangCollege of Precision Instrument and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China.
Menglun ZhangCollege of Precision Instrument and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China.
Xiaodong HuCollege of Precision Instrument and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China.
Wei PangCollege of Precision Instrument and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China.
Xuexin DuanState Key Laboratory of Precision Measuring Technology & Instruments, Tianjin University, Tianjin 300072, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In designing bioassay systems for low-abundance biomolecule detection, most research focuses on improving transduction mechanisms while ignoring the intrinsically fundamental limitations in solution: mass transfer and binding affinity. We demonstrate enhanced biomolecular surface binding using an acoustic nano-electromechanical system (NEMS) resonator, as an on-chip biomolecular concentrator which breaks both mass transfer and binding affinity limitations. As a result, a concentration factor of 10

Identifiers

PMID30062119
PMCPMC6062835

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.