Evidence map›Paper›PMID 30062102›Full record

ArticleNPJ breast cancer2018

Elucidating therapeutic molecular targets in premenopausal Asian women with recurrent breast cancers.

Yoon-Sim Yap, Angad P Singh, John H C Lim, Jin-Hee Ahn, Kyung-Hae Jung, Jeongeun Kim, Rebecca A Dent, Raymond C H Ng, Sung-Bae Kim, Derek Y Chiang

Open access · goldAbstract read
In one paragraph

Article in NPJ breast cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.4field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Yoon-Sim Yap1Division of Medical Oncology, National Cancer Centre, Singapore, Singapore.
Angad P Singh3Oncology Next-Generation Diagnostics, Novartis Institutes for Biomedical Research, Cambridge, USA.
John H C Lim4Department of Clinical Trials and Epidemiological Sciences, National Cancer Centre, Singapore, Singapore.
Jin-Hee Ahn5Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Kyung-Hae Jung5Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Jeongeun Kim5Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Rebecca A Dent1Division of Medical Oncology, National Cancer Centre, Singapore, Singapore.
Raymond C H Ng1Division of Medical Oncology, National Cancer Centre, Singapore, Singapore.
Sung-Bae Kim5Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Derek Y Chiang3Oncology Next-Generation Diagnostics, Novartis Institutes for Biomedical Research, Cambridge, USA.
National Cancer Centre Singapore · SGUniversity of Ulsan · KRAsan Medical Center · KRUlsan College · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is an increasing problem in Asia, with a higher proportion of premenopausal patients who are at higher risk of recurrence. Targeted sequencing was performed on DNA extracted from primary tumor specimens of 63 premenopausal Asian patients who relapsed after initial diagnosis of non-metastatic breast cancer. The most prevalent alterations included:

Identifiers

PMID30062102
PMCPMC6062514
OpenAlexW2794798633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.