Evidence map›Paper›PMID 30062063›Full record

ArticleCell death discovery2018

Combined effects of

Xiangyu Zhou, Mengjia Xu, Weijia Zeng, Zhongzhong Chen, Guohui Lu, Yun Gong, Richard H Finnell, Huasheng Xiao, Bin Qiao, Hongyan Wang

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Cell death discovery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Protein crotonylation: Basic research and clinical diseases.Biochemistry and biophysics reports · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Genetic aberrations and molecular biology of cardiac sarcoma.Therapeutic advances in medical oncology · 2020
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Xiangyu Zhou *1Institute of Reproduction and Development at Obstetrics & Gynecology Hospital, State Key Laboratory of Genetic Engineering at School of Life Sciences, Fudan University, Shanghai, China.
Mengjia Xu *1Institute of Reproduction and Development at Obstetrics & Gynecology Hospital, State Key Laboratory of Genetic Engineering at School of Life Sciences, Fudan University, Shanghai, China.
Weijia Zeng1Institute of Reproduction and Development at Obstetrics & Gynecology Hospital, State Key Laboratory of Genetic Engineering at School of Life Sciences, Fudan University, Shanghai, China.
Zhongzhong Chen1Institute of Reproduction and Development at Obstetrics & Gynecology Hospital, State Key Laboratory of Genetic Engineering at School of Life Sciences, Fudan University, Shanghai, China.
Guohui LuDepartment of Pathology, MD Andersen Cancer Center, Houston, TX USA.
Yun GongDepartment of Pathology, MD Andersen Cancer Center, Houston, TX USA.
Richard H Finnell3Dell Pediatric Research Institute, Department of Pediatrics, The University of Texas at Austin Dell Medical School, Austin, TX USA.
Huasheng XiaoShanghai Biotechnology Corporation, 121 Libing Road, Shanghai, China.
Bin QiaoInstitute of Cardiovascular Disease, General Hospital of Jinan Military Region, Jinan, China.
Hongyan Wang1Institute of Reproduction and Development at Obstetrics & Gynecology Hospital, State Key Laboratory of Genetic Engineering at School of Life Sciences, Fudan University, Shanghai, China.
Fudan University · CNState Key Laboratory of Genetic EngineeringThe University of Texas MD Anderson Cancer Center · USJinan Military General Hospital · CNShanghai CASB Biotechnology (China) · CNThe University of Texas at Austin · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary malignant cardiac tumors (PMCTs) are extremely rare. The apparent immunity of the heart to invasive cancer has attracted considerable interest given the continuously rising incidence of cancer in other organs. This study aims to determine the conditions that could result in cardiac carcinoma and expand our understanding of cardiac tumor occurrence. We report two cases: a male (Patient-1) with primary cardiac malignant fibrous histiocytoma (MFH) and a female (Patient-2) with primary cardiac angiosarcoma. Merged genome-wide analyses of aCGH, Exome sequencing, and RNA-sequencing were performed on Patient-1 using peripheral blood, carcinoma tissue, and samples of adjacent normal tissue. Only whole-transcriptome analysis was carried out on Patient-2, due to insufficient quantities of sample from Patient-2. We identified a novel inherited loss of functional mutation of

Identifiers

PMID30062063
PMCPMC6056498
OpenAlexW2883356874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.