Evidence map›Paper›PMID 30062062›Full record

ArticleCell death discovery2018

Mitochondrial dynamics regulates Drosophila intestinal stem cell differentiation.

Hansong Deng, Shigeo Takashima, Manash Paul, Ming Guo, Volker Hartenstein

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Cell death discovery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
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  3. Science advances · 2025
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  6. Article
  7. Review
  8. c-Jun N-terminal kinase signaling in aging.Frontiers in aging neuroscience · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. The MicroRNAMetabolites · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Mitochondrial Control of Stem Cell State and Fate: Lessons FromFrontiers in cell and developmental biology · 2021
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Hansong Deng *1Shanghai East Hospital, School of Life Sciences and Technology, Tongji University, Shanghai, 20092 China.ORCID 0000-0003-0720-2433
Shigeo Takashima *3Department of Molecular Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA 90095 USA.
Manash Paul3Department of Molecular Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA 90095 USA.
Ming Guo2Department of Neurology, Department of Molecular and Medical Pharmacology, California Nanosystems Institute at UCLA David Geffen School of Medicine, University of California, Los Angeles, CA 90095 USA.
Volker Hartenstein3Department of Molecular Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA 90095 USA.
University of California, Los Angeles · USCalifornia NanoSystems Institute · US

Funding

Lineage-associated wiring properties of Drosphila brain neuronsR01NS054814 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HARTENSTEIN, VOLKER, LOUIS, MATTHIEU R. P. J. C. G. · 2006 to 2025
$6.6M
Studying of pink1/parkin cellular pathway in DrosophilaR01AG033410 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GUO, MING · 2008 to 2012
$1.5M
Genetic Control of Intestinal Stem Cells in the Drosophila HindgutR01GM087373 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HARTENSTEIN, VOLKER · 2009 to 2010
$633k
Developmental and functional analysis of neural circuits controlling navigation in DrosophilaR56NS054814 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HARTENSTEIN, VOLKER, LOUIS, MATTHIEU R. P. J. C. G. · 2021 to 2021
$549k
NIA NIH HHS R01 AG033410NIGMS NIH HHS R01 GM087373NINDS NIH HHS R01 NS054814NINDS NIH HHS R56 NS054814
6 · The paper itself

Abstract

Differentiation of stem/progenitor cells is associated with a substantial increase in mitochondrial mass and complexity. Mitochondrial dynamics, including the processes of fusion and fission, plays an important role for somatic cell reprogramming and pluripotency maintenance in induced pluripotent cells (iPSCs). However, the role of mitochondrial dynamics during stem/progenitor cell differentiation in vivo remains elusive. Here we found differentiation of Drosophila intestinal stem cell is accompanied with continuous mitochondrial fusion. Mitochondrial fusion defective(

Identifiers

PMID30062062
PMCPMC6056485
OpenAlexW2884709538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.