ArticleTranslational neurodegeneration2018
The role of substantia nigra sonography in the differentiation of Parkinson's disease and multiple system atrophy.
Article in Translational neurodegeneration, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Multivariate radiomics models based onEuropean journal of nuclear medicine and molecular imaging · 2021Trial
- Article
- Differences Between Patients With Multiple System Atrophy With Predominant Parkinsonism and Parkinson's Disease Based on fNIRS and Gait Analysis.CNS neuroscience & therapeutics · 2025Article
- The characteristic and biomarker value of transcranial sonography in cerebellar ataxia.Annals of clinical and translational neurology · 2024Article
- The clinical and neuroimaging differences between vascular parkinsonism and Parkinson's disease: a case-control study.BMC neurology · 2024Article
- Simple biomarkers to distinguish Parkinson's disease from its mimics in clinical practice: a comprehensive review and future directions.Frontiers in neurology · 2024Review
- Echogenicity of Brain Structures in Huntington's Disease Patients Evaluated by Transcranial Sonography - Magnetic Resonance Fusion Imaging using Virtual Navigator and Digital Image Analysis.Ultraschall in der Medizin (Stuttgart, Germany : 1980) · 2023Article
- Cognition and transcranial sonography in Parkinson's disease patients with or without orthostatic hypotension.Brain and behavior · 2021Article
- Potential use of corneal confocal microscopy in the diagnosis of Parkinson's disease associated neuropathy.Translational neurodegeneration · 2020Review
- Substantia nigra echogenicity is associated with serum ferritin, gender and iron-related genes in Parkinson's disease.Scientific reports · 2020Article
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12 authors.
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Abstract
backgroundThe differential diagnosis of Parkinson's disease (PD) and multiple system atrophy (MSA) remains a challenge, especially in the early stage. Here, we assessed the value of transcranial sonography (TCS) to discriminate non-tremor dominant (non-TD) PD from MSA with predominant parkinsonism (MSA-P).
methodsEighty-six MSA-P patients and 147 age and gender-matched non-TD PD patients who had appropriate temporal acoustic bone windows were included in this study. All the patients were followed up for at least 2 years to confirm the initial diagnosis. Patients with at least one substantia nigra (SN) echogenic size ≥18 mm
resultsThe frequency of SN hyperechogenicity in non-TD PD patients was significantly higher than that in MSA-P patients (74.1% vs. 38.4%,
conclusionsTCS could help discriminate non-TD PD from MSA-P in a certain extent, but the limitation was also obvious with relatively low specificity, especially in the early stage.
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