ArticleThe Pan African medical journal2018
Severe malaria and death risk factors among children under 5 years at Jason Sendwe Hospital in Democratic Republic of Congo.
Article in The Pan African medical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Prognostic factors in malaria patients with acute kidney injury: a systematic review and meta analysis.Renal failure · 2026Pooled it
- Clinical profiles and predictors of intensive care unit transfer among children hospitalized with severe Plasmodium falciparum malaria in a tertiary care hospital in Libreville, Gabon: a retrospective study.BMC infectious diseases · 2026Article
- Altered natural killer cell function in children with severe malaria.ImmunoHorizons · 2026Article
- Risk factors for malaria-related mortality among children under five at Mbale Regional Referral Hospital, Uganda, 2020-2024: A case-control study.PLOS global public health · 2026Article
- A Cox Proportional Hazards Model Approach to Identifying Malaria Risk Factors in Children in South Sudan.Cureus · 2025Article
- The impact of armed conflict in eastern Democratic Republic of Congo on the risk of malaria outbreaks in children under five years old.New microbes and new infections · 2025Article
- Prevalence and clinical impact of severe anaemia in referral hospitals in southern Benin.Scientific reports · 2025Article
- Article
- Prevalence and factors associated with cerebral malaria among children aged 6 to 59 months with severe malaria in Western Uganda: a hospital-based cross-sectional study.BMC pediatrics · 2024Article
- Risk factors for death among children with severe malaria, Ivukula sub-county, Namutumba district, Eastern Uganda, september 2021-february 2022.Malaria journal · 2024Article
- Under-Five Mortality and Associated Risk Factors in Children Hospitalized at David Bernardino Pediatric Hospital (DBPH), Angola: A Hierarchical Approach.International journal of environmental research and public health · 2024Article
- Severe malaria burden, clinical spectrum and outcomes at Apac district hospital, Uganda: a retrospective study of routine health facility-based data.Malaria journal · 2023Article
- Factors Associated with Severe Malaria among Patients under Reference to District Hospitals: A Cross-Sectional Study in Rusizi District, Rwanda.Rwanda journal of medicine and health sciences · 2023Article
- Article
- Transcriptional Profiles Analysis of COVID-19 and Malaria Patients Reveals Potential Biomarkers in Children.bioRxiv : the preprint server for biology · 2022Article
- Self-medication and Anti-malarial Drug Resistance in the Democratic Republic of the Congo (DRC): A silent threat.Tropical medicine and health · 2022Review
- Key factors predicting suspected severe malaria case management and health outcomes: an operational study in the Democratic Republic of the Congo.Malaria journal · 2022Observational
- Factors influencing severity of recurrent malaria in a conflict-affected state of South Sudan: an unmatched case-control study.Conflict and health · 2022Article
- Treatment outcome and factors associated with mortality due to malaria in Munini District Hospital, Rwanda in 2016-2017: Retrospective cross-sectional study.Frontiers in public health · 2022Article
- Profiling malaria infection among under-five children in the Democratic Republic of Congo.PloS one · 2021Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMalaria is still a major public health concern in the Democratic Republic of Congo. Its morbidity and mortality challenge the actual strategies of the fight agains malaria. This study was aimed to describe the epidemiology, the clinical caracteristics and the risk factors of death associated to severe malaria in the pediatric population under 5 years at Sendwe Hospital of Lubumbashi.
methodsThis analytical retrospective study was conducted in Lubumbashi, in the province of Haut-Katanga. All patients under 5 years hospitalized for severe malaria were registered from January 2014 to December 2016.
resultsAmong the 3,092 patients hospitalised during our study period, 452 (14.6%) were admitted for severe malaria. The average age was 27.04 months, the male sex was the most affected (53.54% with the sex-ratio 1.15). The most frequent forms of gravity noticed were cerebral malaria (48.23%) and severe anemia (46.90%). Death was noted in the evolution in 28.32%. Repeated convulsion (OR = 2.27; 95% CI: 1.47-3.48), coma (OR = 3.55; 95% CI: 2.19-5.74) and severe acute malnutrition (OR = 3.32; 95% CI: 1.56-7.06) were asscociated with a high risk of death.
conclusionThis research shows that severe malaria is still an important cause of morbidity and mortality among young children in Lubumbashi. Neurologic and anemic forms are the most frequent. The predictive signs of death are: repeated convulsions, coma and severe acute malnutrition.
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