Evidence map›Paper›PMID 30061932›Full record

ArticleBiotechnology for biofuels2018

Metabolic engineering of

Bakht Zada, Chonglong Wang, Ji-Bin Park, Seong-Hee Jeong, Ju-Eon Park, Hawaibam Birla Singh, Seon-Won Kim

Open access · goldAbstract read
In one paragraph

Article in Biotechnology for biofuels, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 72 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Advances in regulating vitamin KWorld journal of microbiology & biotechnology · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Microbial Production, Extraction, and Quantitative Analysis of Isoprenoids.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. The isoprenoid alcohol pathway, a synthetic route for isoprenoid biosynthesis.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Bakht Zada *1Division of Applied Life Science (BK21 Plus Program), PMBBRC, Gyeongsang National University, Jinju, 52828 Republic of Korea.
Chonglong Wang *2School of Biology and Basic Medical Sciences, Soochow University, Suzhou, People's Republic of China.
Ji-Bin Park1Division of Applied Life Science (BK21 Plus Program), PMBBRC, Gyeongsang National University, Jinju, 52828 Republic of Korea.
Seong-Hee Jeong1Division of Applied Life Science (BK21 Plus Program), PMBBRC, Gyeongsang National University, Jinju, 52828 Republic of Korea.
Ju-Eon Park1Division of Applied Life Science (BK21 Plus Program), PMBBRC, Gyeongsang National University, Jinju, 52828 Republic of Korea.
Hawaibam Birla Singh1Division of Applied Life Science (BK21 Plus Program), PMBBRC, Gyeongsang National University, Jinju, 52828 Republic of Korea.
Seon-Won Kim1Division of Applied Life Science (BK21 Plus Program), PMBBRC, Gyeongsang National University, Jinju, 52828 Republic of Korea.
Gyeongsang National University · KRSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrent petroleum-derived fuels such as gasoline (C

resultsIn this study, the promiscuous activity of NudB toward geranyl diphosphate (GPP) and farnesyl diphosphate (FPP) was applied for the production of isoprenoid alcohol mixtures, including isopentenol, geraniol, and farnesol, and their derivatives.

conclusionsThe promiscuous activity of NudB was newly identified and successfully used for production of isoprenoid-based alcohol mixtures, which are suitable as next-generation biofuels or commodity chemicals. This is the first successful report on high-titer production of an isoprenoid alcohol-based mixture. The engineering approaches can provide a valuable platform for production of other isoprenoid mixtures via a proportional modulation of IPP, DMAPP, GPP, and FPP syntheses.

Indexed as

Escherichia coliFarnesolGeraniolIsopentenolIsoprenoid mixtureNudB

Identifiers

PMID30061932
PMCPMC6058358
OpenAlexW2884672223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.