Evidence map›Paper›PMID 30061896›Full record

ReviewFrontiers in immunology2018

Potential Pathways Associated With Exaggerated T Follicular Helper Response in Human Autoimmune Diseases.

Shu Horiuchi, Hideki Ueno

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Observational
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shu HoriuchiDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Hideki UenoDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

Funding

Scientific CoreU19AI082715 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI PASCUAL, MARIA VIRGINIA · 2009 to 2018
$6.4M
NIAID NIH HHS U19 AI082715
6 · The paper itself

Abstract

Convincing lines of evidence in both mice and humans show that exaggerated T follicular helper (Tfh) responses is pathogenic in autoimmune diseases. However, the cause of exaggerated Tfh response in humans is still much less clear than in mouse models where genetic factors can be manipulated for

Indexed as

autoimmune diseasesIL-12IL-23IRF5STAT4T follicular helperTNFSF4ustekinumab

Identifiers

PMID30061896
PMCPMC6054970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.