ArticleActa informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH2018
Effect of Low-level Laser Therapy on Orthodontic Movement of Human Canine: a Systematic Review and Meta-analysis of Randomized Clinical Trials.
Article in Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05766618 (The Effect of Multiple Injections of Platelets Rich Fibrin), which is not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Multiple Injections of Platelets Rich Fibrin (i-PRF) on The Rate of Canine Retraction A Split-mouth: A Randomized Controlled Trial
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Umbrella review of photobiomodulation/low-level laser therapy and vitamin D in orthodontics: effects on tooth movement, pain, root resorption, and bone biomarkers.BMC oral health · 2026Pooled it
- Effectiveness of photobiomodulation with low-level lasers on the acceleration of orthodontic tooth movement: an umbrella review.Evidence-based dentistry · 2025Pooled it
- Effect of 970 nm low-level laser therapy on orthodontic tooth movement during Class II intermaxillary elastics treatment: a RCT.Scientific reports · 2021Trial
- Photobiomodulation in orthodontics: an overview of systematic reviews with meta-regression and evidence map.Odontology · 2026Review
- The Effectiveness of Physical Adjunctive Interventions in the Acceleration of Orthodontic Tooth Movement: An Umbrella Review and Meta-Analysis.International journal of dentistry · 2026Review
- Photobiomodulation Meets Mechanotransduction: Immune-Stromal Crosstalk in Orthodontic Remodeling.Biomedicines · 2025Review
- Effect of 980nm Low-Level Laser Therapy on Matrix Metalloproteinase-1 Levels in Gingival Crevicular Fluid During Fixed Orthodontic Treatment.Journal of lasers in medical sciences · 2025Article
- Accelerated Orthodontic Treatment using Biomodulation: A Randomized Clinical Trial.Journal of pharmacy & bioallied sciences · 2024Article
- Article
- Predictability of InvisalignDentistry journal · 2022Article
- Review
- Orthodontic Bracket Removal Using LASER-Technology-A Short Systematic Literature Review of the Past 30 Years.Materials (Basel, Switzerland) · 2022Review
- Perception of Iraqi Orthodontists and Patients toward Accelerated Orthodontics.International journal of dentistry · 2021Article
- Efficacy of Laser Photobiomodulation in Accelerating Orthodontic Tooth Movement in Children: A Systematic Review with Meta-analysis.International journal of clinical pediatric dentistry · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLow-level Laser Therapy (LLLT) is a noninvasive method of accelerating tooth movement. Herein, this meta-analysis was aimed to assess the efficacy of LLLT in accelerating orthodontic
methodsFive databases including Web of Science, Scopus, PubMed, ScienceDirect, and Cochrane Library were used for searching the studies. Studies on LLLT for orthodontic tooth movement of human canine, randomized clinical trial (RCT), and outcome variables such as distance or speed of the tooth movement in treatment duration were considered for the final analysis. RevMan 5.3 was used for calculating the mean difference (MD) and 95% confidence intervals (CIs) on random-effects model.
resultsOut of 275 studies retrieved from five databases, six RCTs were included and analyzed in this meta-analysis. The results showed that the orthodontic movement of canine was statistically increased in the LLLT group compared with the control group in 21 days (MD: 0.74; 95%CI: 0.17, 1.31; P = 0.01), one month (MD: 0.40; 95%CI: 0.10, 0.69; P = 0.008), 1.5 months (MD: 0.72; 95%CI: 0.51, 0.93; P < 00001), two months (MD: 0.84; 95%CI: 0.23, 1.44; P = 0.006) three months (MD: 0.92; 95%CI: 0.06, 1.78; P = 0.04), and 4.5 months (MD: 1.53; 95%CI: 0.92, 2.14; P < 0.00001).
conclusionThe LLLT can speed up the rate of tooth movement of human canine and consequently decrease the treatment time. LLLT represents a proper adjuvant therapy for fixed orthodontic treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.