ArticleScientific reports2018
In situ phase contrast X-ray brain CT.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Phase and absorbance retrieval in X-ray holographic microscopy under weak illumination using physics-driven neural networks.Journal of synchrotron radiation · 2026Article
- Quantitative Stain Mapping in X-Ray Virtual Histology.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- For your eyes too: a new set of images of biological materials from the scientific commissioning of the MOGNO beamline at Sirius.Journal of synchrotron radiation · 2026Article
- 3DMPR - a robust morphological approach for applying phase retrieval in proximity to highly attenuating objects in computed tomography.Journal of synchrotron radiation · 2025Article
- Development of a deep learning method for phase retrieval image enhancement in phase contrast microcomputed tomography.Journal of microscopy · 2025Article
- Low-dose, high-resolution CT of infant-sized lungs via propagation-based phase contrast.Scientific reports · 2025Article
- Synchrotron Radiation-Based Tomography of an Entire Mouse Brain with Sub-Micron Voxels: Augmenting Interactive Brain Atlases with Terabyte Data.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- The potential of x-ray virtual histology in the diagnosis of skin tumors.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024Article
- X-ray phase contrast reveals soft tissue and shell growth lines in mollusks.Communications biology · 2024Article
- Multi-resolution X-ray phase-contrast and dark-field tomography of human cerebellum with near-field speckles.Biomedical optics express · 2024Article
- Tomographic detection of photon pairs produced from high-energy X-rays for the monitoring of radiotherapy dosing.Nature biomedical engineering · 2023Article
- Precise phase retrieval for propagation-based images using discrete mathematics.Scientific reports · 2022Article
- High-Resolution X-ray Phase-Contrast Imaging and Sensory and Rheometer Tests in Cooked Edamame.Foods (Basel, Switzerland) · 2022Article
- Early Diagnosis and Real-Time Monitoring of Regional Lung Function Changes to Prevent Chronic Obstructive Pulmonary Disease Progression to Severe Emphysema.Journal of clinical medicine · 2021Review
- Three-dimensional virtual histology of the cerebral cortex based on phase-contrast X-ray tomography.Biomedical optics express · 2021Article
- Three-dimensional virtual histology of the human hippocampus based on phase-contrast computed tomography.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Single-Shot Multicontrast X-ray Imaging for In Situ Visualization of Chemical Reaction Products.Journal of imaging · 2021Article
- Article
- Dual-energy phase retrieval algorithm for inline phase sensitive x-ray imaging system.Optics express · 2021Article
- Correlation of image quality parameters with tube voltage in X-ray dark-field chest radiography: a phantom study.Scientific reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
Phase contrast X-ray imaging (PCXI) is an emerging imaging modality that has the potential to greatly improve radiography for medical imaging and materials analysis. PCXI makes it possible to visualise soft-tissue structures that are otherwise unresolved with conventional CT by rendering phase gradients in the X-ray wavefield visible. This can improve the contrast resolution of soft tissues structures, like the lungs and brain, by orders of magnitude. Phase retrieval suppresses noise, revealing weakly-attenuating soft tissue structures, however it does not remove the artefacts from the highly attenuating bone of the skull and from imperfections in the imaging system that can obscure those structures. The primary causes of these artefacts are investigated and a simple method to visualise the features they obstruct is proposed, which can easily be implemented for preclinical animal studies. We show that phase contrast X-ray CT (PCXI-CT) can resolve the soft tissues of the brain in situ without a need for contrast agents at a dose ~400 times lower than would be required by standard absorption contrast CT. We generalise a well-known phase retrieval algorithm for multiple-material samples specifically for CT, validate its use for brain CT, and demonstrate its high stability in the presence of noise.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.