ArticleScientific reports2018
Exploring Cuba's population structure and demographic history using genome-wide data.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Decentralisation of the Healthcare Systems and the Functioning of Public Health Programmes in Single-Party States: A Systematic Review.The International journal of health planning and management · 2026Pooled it
- Meta-analysis of GWA studies provides new insights on the genetic architecture of skin pigmentation in recently admixed populations.BMC genetics · 2019Pooled it
- HOROSCOPE: Decoding human centromere architecture from short reads usingbioRxiv : the preprint server for biology · 2026Article
- Polymorphisms in DNA repair related genes as risk factors for lung cancer in Cuban population: a case control study.BMC cancer · 2025Article
- Egypt Genome: Towards an African new genomic era.Journal of advanced research · 2025Review
- Genetic analysis and natural history of Parkinson's disease due to the LRRK2 G2019S variant.Brain : a journal of neurology · 2024Article
- The Global Evolutionary History of Orf Virus in Sheep and Goats Revealed by Whole Genomes Data.Viruses · 2024Article
- Prevalence of single-nucleotide variants in twenty-five pharmacogenes from a Cuban sample cohort.Frontiers in pharmacology · 2024Article
- Neuropsychiatric features in a multi-ethnic population with Alzheimer disease and mild cognitive impairment.International journal of geriatric psychiatry · 2023Article
- A genetic and linguistic analysis of the admixture histories of the islands of Cabo Verde.eLife · 2023Article
- A review of ancestrality and admixture in Latin America and the caribbean focusing on native American and African descendant populations.Frontiers in genetics · 2023Review
- Caribbean Latinx with moderate-severe asthma bear greater asthma morbidity than other Latinx.The Journal of allergy and clinical immunology · 2022Article
- Complex genetic admixture histories reconstructed with Approximate Bayesian Computation.Molecular ecology resources · 2021Article
- A genetic history of the pre-contact Caribbean.Nature · 2021Article
- Article
- Gene flow as a simple cause for an excess of high-frequency-derived alleles.Evolutionary applications · 2020Article
- Genetic Consequences of the Transatlantic Slave Trade in the Americas.American journal of human genetics · 2020Article
- Reconstructed Lost Native American Populations from Eastern Brazil Are Shaped by Differential Jê/Tupi Ancestry.Genome biology and evolution · 2019Article
- A Transient Pulse of Genetic Admixture from the Crusaders in the Near East Identified from Ancient Genome Sequences.American journal of human genetics · 2019Article
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12 authors.
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Abstract
Cuba is the most populated country in the Caribbean and has a rich and heterogeneous genetic heritage. Here, we take advantage of dense genomic data from 860 Cuban individuals to reconstruct the genetic structure and ancestral origins of this population. We found distinct admixture patterns between and within the Cuban provinces. Eastern provinces have higher African and Native American ancestry contributions (average 26% and 10%, respectively) than the rest of the Cuban provinces (average 17% and 5%, respectively). Furthermore, in the Eastern Cuban region, we identified more intense sex-specific admixture patterns, strongly biased towards European male and African/Native American female ancestries. Our subcontinental ancestry analyses in Cuba highlight the Iberian population as the best proxy European source population, South American and Mesoamerican populations as the closest Native American ancestral component, and populations from West Central and Central Africa as the best proxy sources of the African ancestral component. Finally, we found complex admixture processes involving two migration pulses from both Native American and African sources. Most of the inferred Native American admixture events happened early during the Cuban colonial period, whereas the African admixture took place during the slave trade and more recently as a probable result of large-scale migrations from Haiti.
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