Evidence map›Paper›PMID 30061600›Full record

ArticleNature structural & molecular biology2018

Mechanisms of genetic instability caused by (CGG)

Artem V Kononenko, Thomas Ebersole, Karen M Vasquez, Sergei M Mirkin

Abstract read
In one paragraph

Article in Nature structural & molecular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 44 citations in OpenAlex.

  1. Mechanisms and genomic implications of break-induced replication.Nature structural & molecular biology · 2025
    Review
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  14. Creation and resolution of non-B-DNA structural impediments during replication.Critical reviews in biochemistry and molecular biology · 2022
    Article
  15. Article
  16. Mechanisms of theInternational journal of molecular sciences · 2022
    Review
  17. Article
  18. ReducedFrontiers in cell and developmental biology · 2022
    Article
  19. Homologous recombination within repetitive DNA.Current opinion in genetics & development · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Artem V KononenkoDepartment of Biology, Tufts University, Medford, MA, USA.
Thomas EbersoleDepartment of Biology, Tufts University, Medford, MA, USA.
Karen M VasquezDivision of Pharmacology and Toxicology, College of Pharmacy, University of Texas, Austin, TX, USA.
Sergei M MirkinDepartment of Biology, Tufts University, Medford, MA, USA. sergei.mirkin@tufts.edu.ORCID http://orcid.org/0000-0003-4576-7582
Tufts University · USThe University of Texas at Austin · US

Funding

Mutations Arising During DNA RepairP01GM105473 · NIGMS · BRANDEIS UNIVERSITY · PI HABER, JAMES E · 2014 to 2018
$8.6M
REPAIR OF GENOME DESTABILIZING DNA STRUCTURESR01CA093729 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Karen M Vasquez · 2002 to 2026
$8.2M
REPLICATION OF SIMPLE DNA REPEATSR01GM060987 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MIRKIN, SERGEI · 2001 to 2017
$4.9M
NCI NIH HHS R01 CA093729NIGMS NIH HHS P01 GM105473NIGMS NIH HHS R01 GM060987
6 · The paper itself

Abstract

We developed an experimental system for studying genome instability caused by fragile X (CGG)

Indexed as

Genomic InstabilityTrinucleotide RepeatsAnimalsCells, CulturedDNA ReplicationFragile X Messenger Ribonucleoprotein 1HumansMammalsMiceMutationPromoter Regions, GeneticFMR1 protein, humanFragile X Messenger Ribonucleoprotein 1

Identifiers

PMID30061600
PMCPMC6082162
OpenAlexW2883315334

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.