Evidence map›Paper›PMID 30061589›Full record

Observational studyJournal of perinatology : official journal of the California Perinatal Association2018

Thyroid gland volumes in premature infants using serial ultrasounds.

Safdar S Khan, Irene Hong-McAtee, Vesna Martich Kriss, Scott Stevens, Timothy Crawford, Mina Hanna, Henrietta Bada, Nirmala Desai

Registry-linked trialOpen access · bronzeAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Journal of perinatology : official journal of the California Perinatal Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04208503 (Ultrasound and Functional Thyroid Evaluation in Preterm Infants Born Between 24 and 32 Weeks of Gestation), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04208503 unknown statusnot on this mapstarted 2019, after this paper: background citation

Ultrasound and Functional Thyroid Evaluation in Preterm Infants Born Between 24 and 32 Weeks of Gestation

Typeobservational_patient_registrySponsorPrincess Anna Mazowiecka Hospital, Warsaw, PolandRan2019 to 2021Enrolled200ConditionsThyroid, Gland, Functional DisturbanceArmsthyroid ultrasound
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Safdar S KhanUniversity of Kentucky, Lexington, KY, USA. ssk87@miami.edu.
Irene Hong-McAteeVanderbilt University, Nashville, TN, USA.
Vesna Martich KrissNorton Children's Hospital, Louisville, KY, USA.
Scott StevensUniversity of Kentucky, Lexington, KY, USA.
Timothy CrawfordWright State University Boonshoft School of Medicine, Dayton, OH, USA.
Mina HannaUniversity of Kentucky, Lexington, KY, USA.
Henrietta BadaUniversity of Kentucky, Lexington, KY, USA.
Nirmala DesaiUniversity of Kentucky, Lexington, KY, USA.
University of Kentucky · USKosair Children's Hospital · USVanderbilt University · USWright State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is a gap in knowledge about the postnatal growth of thyroid gland in preterm infants.

objectiveTo determine postnatal growth of thyroid gland in preterm infants.

methodsThyroid gland volume was calculated in 57 prospectively enrolled preterm infants by measuring serial longitudinal, antero-posterior, and transverse dimensions of thyroid gland with ultrasound. Data were analyzed by using the Wilcoxon and independent t test.

resultsThere was a significant correlation between thyroid volume (TV) and birthweight (BW) (p = 0.01), and between TV and gestational age (p = 0.02). However, unexpectedly, 12 infants had a decrease in TV between the first and second ultrasounds. Infants with late onset bacterial sepsis had lower TVs on their second ultrasounds than infants without sepsis.

conclusionsThyroid ultrasound in preterm infants provides noninvasive and quick approach to determine TV and morphology. TV in preterm infants correlates positively with BW and gestational age. However, postnatal growth of thyroid gland is variable and may seemingly be affected by postnatal factors.

Indexed as

Infant, PrematureBirth WeightFemaleGestational AgeHumansInfant, NewbornMaleNeonatal SepsisPregnancyProspective StudiesThyroid GlandThyroxineUltrasonographyThyroxine

Identifiers

PMID30061589
OpenAlexW2884551316

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.