Evidence map›Paper›PMID 30061411›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

In vivo replacement of damaged bladder urothelium by Wolffian duct epithelial cells.

Diya B Joseph, Anoop S Chandrashekar, Lisa L Abler, Li-Fang Chu, James A Thomson, Cathy Mendelsohn, Chad M Vezina

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  10. Article
  11. DNA methylation in development and disease: an overview for prostate researchers.American journal of clinical and experimental urology · 2018
    Review
  12. Development of the human prostate.Differentiation; research in biological diversity
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Diya B JosephDepartment of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706.
Anoop S ChandrashekarDepartment of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706.
Lisa L AblerDepartment of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706.
Li-Fang ChuMorgridge Institute for Research, Madison, WI 53715.ORCID 0000-0002-4738-4481
James A ThomsonMorgridge Institute for Research, Madison, WI 53715.
Cathy MendelsohnDepartment of Urology, Columbia University, New York, NY 10032.
Chad M VezinaDepartment of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706; chad.vezina@wisc.edu.ORCID 0000-0001-7058-5399
University of Wisconsin–Madison · USColumbia University · US

Funding

Transcriptional Regulation of Urothelial Differentiation During Homeostasis and Repair in Response to Urinary Tract InfectionU54DK104309 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI JONATHAN M. BARASCH, ALI G GHARAVI · 2014 to 2026
$17.7M
Role of Beta-Catenin in Urinary DysfunctionU54DK104310 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI MACOSKA, JILL A., MARKER, PAUL C · 2014 to 2023
$12.8M
Retinoic acid signaling controls urothelial development and regeneration.R01DK095044 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MENDELSOHN, CATHY LEE · 2013 to 2021
$3.5M
Role of DNA methylation in prostate glandular development and urinary functionR01DK099328 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI VEZINA, CHAD M. · 2014 to 2018
$1.6M
Molecular and fate maps of prostatic stromaU01DK110807 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI VEZINA, CHAD M. · 2016 to 2020
$1.6M
NIDDK NIH HHS R01 DK095044NIDDK NIH HHS R01 DK099328NIDDK NIH HHS U01 DK110807NIDDK NIH HHS U54 DK104309NIDDK NIH HHS U54 DK104310
6 · The paper itself

Abstract

The bladder's remarkable regenerative capacity had been thought to derive exclusively from its own progenitors. While examining consequences of DNA methyltransferase 1 (

Indexed as

AnimalsAnimals, NewbornApoptosisCell LineageDNA (Cytosine-5-)-Methyltransferase 1DNA DamageDNA MethylationEpithelial CellsMiceRegenerationUrinary BladderUrotheliumWolffian DuctsDNA (Cytosine-5-)-Methyltransferase 1Dnmt1 protein, mouseapoptosisbladderDNMT1regenerationWolffian duct

Identifiers

PMID30061411
PMCPMC6099915
OpenAlexW2885671943

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.