Evidence map›Paper›PMID 30061410›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Double-stranded RNA binding protein, Staufen, is required for the initiation of RNAi in coleopteran insects.

June-Sun Yoon, Kanakachari Mogilicherla, Dhandapani Gurusamy, Xien Chen, Shankar C R R Chereddy, Subba Reddy Palli

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 137 citations in OpenAlex.

  1. Article
  2. Article
  3. Hl48 modulates argonaute 2 to enhance RNA interference in ticks.Frontiers in cellular and infection microbiology · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. StaufenC facilitates utilization of the ERAD pathway to transport dsRNA through the endoplasmic reticulum to the cytosol.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  12. Article
  13. Article
  14. Identification of Potential Gene Targets for Suppressing Oviposition inInternational journal of molecular sciences · 2023
    Article
  15. Article
  16. The Formation and Function ofInternational journal of molecular sciences · 2023
    Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

June-Sun YoonDepartment of Entomology, College of Agriculture, Food and Environment, University of Kentucky, Lexington, KY 40546.
Kanakachari MogilicherlaDepartment of Entomology, College of Agriculture, Food and Environment, University of Kentucky, Lexington, KY 40546.
Dhandapani GurusamyDepartment of Entomology, College of Agriculture, Food and Environment, University of Kentucky, Lexington, KY 40546.
Xien ChenDepartment of Entomology, College of Agriculture, Food and Environment, University of Kentucky, Lexington, KY 40546.
Shankar C R R ChereddyDepartment of Entomology, College of Agriculture, Food and Environment, University of Kentucky, Lexington, KY 40546.
Subba Reddy PalliDepartment of Entomology, College of Agriculture, Food and Environment, University of Kentucky, Lexington, KY 40546 rpalli@uky.edu.
University of Kentucky · US

Funding

Molecular Analysis of Juvenile Hormone ActionR01GM070559 · NIGMS · UNIVERSITY OF KENTUCKY · PI PALLI, SUBBA R · 2005 to 2024
$4.1M
RNAi methods for Zika virus vector controlR21AI131427 · NIAID · UNIVERSITY OF KENTUCKY · PI PALLI, SUBBA R · 2017 to 2018
$385k
NIAID NIH HHS R21 AI131427NIGMS NIH HHS R01 GM070559
6 · The paper itself

Abstract

RNA interference (RNAi) is being used to develop methods to control pests and disease vectors. RNAi is robust and systemic in coleopteran insects but is quite variable in other insects. The determinants of efficient RNAi in coleopterans, as well as its potential mechanisms of resistance, are not known. RNAi screen identified a double-stranded RNA binding protein (StaufenC) as a major player in RNAi. StaufenC homologs have been identified in only coleopteran insects. Experiments in two coleopteran insects,

Indexed as

RNA InterferenceAnimalsColeopteraInsect ProteinsRNA-Binding ProteinsRNA, Double-StrandedInsect ProteinsRNA-Binding ProteinsRNA, Double-StrandedLeptinotarsaresistanceRNAi efficiencysiRNATribolium

Identifiers

PMID30061410
PMCPMC6099913
OpenAlexW2885524011

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.