Evidence map›Paper›PMID 30061406›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Mutations in the

Brandon S Dunn, Lindsay Rush, Jin-Yu Lu, Tian Xu

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Drosophila as a Model for Metastasis.Advances in experimental medicine and biology · 2025
    Review
  7. Article
  8. Review
  9. Hinfp is a guardian of the somatic genome by repressing transposable elements.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Brandon S DunnHoward Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510.ORCID 0000-0003-4374-0968
Lindsay RushHoward Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510.
Jin-Yu LuHoward Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510.
Tian XuHoward Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510; tian.xu@yale.edu.
Howard Hughes Medical Institute · US

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

Complications from metastasis are responsible for the majority of cancer-related deaths. Despite the outsized medical impact of metastasis, remarkably little is known about one of the key early steps of metastasis: departure of a tumor cell from its originating tissue. It is well documented that cellular delamination in the basal direction can induce invasive behaviors, but it remains unknown if apical cell delamination can induce migration and invasion in a cancer context. To explore this feature of cancer progression, we performed a genetic screen in

Indexed as

MutationNeoplasm InvasivenessAnimalsCell MovementDrosophila melanogasterDrosophila ProteinsIntercellular JunctionsMyosin Type IINeoplasm Metastasisras ProteinsrhoA GTP-Binding ProteinDrosophila ProteinsMyosin Type IIras ProteinsrhoA GTP-Binding Proteincancercell delaminationDrosophilainvasiontricellular junctions

Identifiers

PMID30061406
PMCPMC6099892
OpenAlexW2885735231

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.