Evidence map›Paper›PMID 30061378›Full record

ArticleInfection and immunity2018

Coxiella burnetii Blocks Intracellular Interleukin-17 Signaling in Macrophages.

Tatiana M Clemente, Minal Mulye, Anna V Justis, Srinivas Nallandhighal, Tuan M Tran, Stacey D Gilk

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 33 citations in OpenAlex.

  1. Trial
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  7. Pathogens (Basel, Switzerland) · 2025
    Article
  8. Bacterial Puppeteering: How the Stealth BacteriumPathogens (Basel, Switzerland) · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Caspase-8 activity mediates TNFα production and restrictsbioRxiv : the preprint server for biology · 2024
    Article
  13. Article
  14. TheProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tatiana M ClementeDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Minal MulyeDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Anna V JustisDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Srinivas NallandhighalDivision of Infectious Diseases, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Tuan M TranDivision of Infectious Diseases, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Stacey D GilkDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA sgilk@iu.edu.ORCID https://orcid.org/0000-0002-0835-057X
Indiana University School of Medicine

Funding

Immunology and Infectious Diseases Training ProgramT32AI060519 · NIAID · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI MARK H KAPLAN · 2004 to 2026
$6.0M
Defining clinical and sterile immunity to Plasmodium falciparum infection using systems biology approachesK08AI125682 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI TRAN, TUAN MANH · 2017 to 2021
$926k
Reprogramming of host cell cholesterol homeostasis by Coxiella burnetiiR21AI121786 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI GILK, STACEY D · 2016 to 2017
$423k
NIAID NIH HHS K08 AI125682NIAID NIH HHS R21 AI121786NIAID NIH HHS T32 AI060519
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBacterial ProteinsChemokine CXCL2Coxiella burnetiiHost-Pathogen InteractionsHumansInterleukin-1Interleukin-17MacrophagesMice, Inbred C57BLQ FeverSignal TransductionType IV Secretion SystemsBacterial ProteinsChemokine CXCL2Interleukin-1Interleukin-17Type IV Secretion SystemsCoxiella burnetiiIL-17innate immunitymacrophagetype 4 secretion

Identifiers

PMID30061378
PMCPMC6204741
OpenAlexW2891922975

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.