Evidence map›Paper›PMID 30061290›Full record

ArticleAntimicrobial agents and chemotherapy2018

Sulfide Protects Staphylococcus aureus from Aminoglycoside Antibiotics but Cannot Be Regarded as a General Defense Mechanism against Antibiotics.

Julia Weikum, Niklas Ritzmann, Nils Jelden, Anna Klöckner, Sebastian Herkersdorf, Michaele Josten, Hans-Georg Sahl, Fabian Grein

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Effect of HArchives of microbiology · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Hydrogen Sulfide and Carbon Monoxide Tolerance in Bacteria.Antioxidants (Basel, Switzerland) · 2021
    Review
  12. Review
  13. Article
  14. Hydrogen Sulfide SensitizesFrontiers in microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Julia Weikum *Institute for Pharmaceutical Microbiology, University Hospital Bonn, University of Bonn, Bonn, Germany.
Niklas Ritzmann *Institute for Pharmaceutical Microbiology, University Hospital Bonn, University of Bonn, Bonn, Germany.
Nils JeldenInstitute for Pharmaceutical Microbiology, University Hospital Bonn, University of Bonn, Bonn, Germany.
Anna KlöcknerInstitute for Pharmaceutical Microbiology, University Hospital Bonn, University of Bonn, Bonn, Germany.
Sebastian HerkersdorfInstitute for Pharmaceutical Microbiology, University Hospital Bonn, University of Bonn, Bonn, Germany.
Michaele JostenInstitute for Pharmaceutical Microbiology, University Hospital Bonn, University of Bonn, Bonn, Germany.
Hans-Georg SahlGerman Center for Infection Research, Bonn-Cologne Site, Bonn, Germany.
Fabian GreinInstitute for Pharmaceutical Microbiology, University Hospital Bonn, University of Bonn, Bonn, Germany grein@uni-bonn.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sulfide production has been proposed to be a universal defense mechanism against antibiotics in bacteria (K. Shatalin, E. Shatalina, A. Mironov, and E. Nudler, Science 334:986-990, 2011, doi:10.1126/science.1209855). To gain insight into the mechanism underlying sulfide protection, we systematically and comparatively addressed the interference of sulfide with antibiotic activity against

Indexed as

AminoglycosidesAnti-Bacterial AgentsDrug Resistance, BacterialMicrobial Sensitivity TestsStaphylococcus aureusSulfidesAminoglycosidesAnti-Bacterial AgentsSulfidesaminoglycosidesresistance mechanismsStaphylococcus aureus

Identifiers

PMID30061290
PMCPMC6153802

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.